HYSTERIA Evaluation of Clinical HYpnosis After Surgical Resection for Crohn Disease on Post-operative Analgesia

Prospective Randomized Study Evaluating the Effect of Pre-operative Hypnosis on Anesthesia, Analgesia and Perioperative Stress Laparoscopic Ileo-caecal Resections of Crohn's Disease.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03261414

Acronym

HYSTERIA

Enrollment

Registered

2017-08-25

Start date

2015-05-27

Completion date

2020-01-30

Last updated

2021-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Inflammatory Bowel Diseases

Brief summary

The aim of this study will be to show a decrease in postoperative morphine consumption by the practice of perioperative self-hypnosis in patients undergoing laparoscopic ileo-caecal resection for Crohn's disease

Interventions

PROCEDUREHypnosis

A short preanesthetic hypnosis before induction of anesthesia

PROCEDUREusual care

Standard care before induction of anesthesia

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Being affected by a crohn's disease, reaching the small intestine (ileal or ileo-colic) and requiring ileo-caecal resection by laparoscopy * Never been operated for abdominal crohn's disease

Exclusion criteria

* Pregnant women * A history of intestinal resection for crohn's disease * Emergency surgery * Corticotherapy in progress * Deaf patients * non-Francophone Patients * Patients with knowledge of self-hypnosis

Design outcomes

Primary

Measure	Time frame	Description
Total morphine consumption	During the first 24 postoperative hours	Compare the cumulative morphine consumption during 24 hours postoperative Data from PCA pump and patient medical record

Secondary

Measure	Time frame	Description
Total number of patients with complications	during first 7 postoperative days	—
Intraoperative consumption of hypnotics and opioids	during first 7 postoperative days	The hypnotics and opioids drug dose will be recorded
Antiemetics consumption	during first 7 postoperative days	The antiemetic drug dose will be recorded
Total morphine consumption	between the 24 and the 48 postoperative hours	Compare the cumulative morphine consumption between the 24 and the 48 postoperative hours Data from PCA pump and patient medical record
Duration of hospital stay	during first 7 postoperative days	—
Time physiological function recovery	during first 7 postoperative days	Ability to drink, to eat, to urinate, to walk
Postoperative nausea and vomiting (PONV) Score	first 24 postoperative hours	PONV risk assessment tool Based on apfel's simplified risk score

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026