Exercise-induced Inflammation
Conditions
Brief summary
The aim of the study is to determine whether fish oil (specifically omega-3 long chain polyunsaturated fatty acids \[EPA-DHA\]) supplementation can enhance eccentric resistance exercise performance when combined with a resistance exercise training study. The investigators aim to establish the potential mechanisms that might mediate performance changes at a cellular level.
Interventions
DIETARY_SUPPLEMENTFish Oil
Fish Oil Capsule
DIETARY_SUPPLEMENTPlacebo
Olive Oil capsule manufactured to mimic fish oil capsule
Sponsors
Loughborough University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
MALE
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Males * Healthy
Exclusion criteria
* Resistance exercise training within the past 6 months * Vitamin or fish oil supplementation over the past 6 months * Habitual use of anti-inflammatory drugs * History of heart disease * History of coagulation/bleeding disorder * History of metabolic disease * Serious allergy * Known to have blood-borne virus * Females (Due to differences in cell membrane incorporation of Omega-3 between the sexes and the testing schedule being unable to fit in with menstrual cycle, altering the blood markers that are being measured) * Currently no symptoms of general illness
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Strength | Change from baseline strength at 11 weeks | Quadriceps and Hamstring strength using an isokinetic dynamometer |
| Leg power | Change from baseline strength at 11 weeks | Dynamic leg power assessed through jump height on force platform |
Countries
United Kingdom
Outcome results
None listed