Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes

Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes in CHNS

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03259321

Enrollment

15100

Registered

2017-08-23

Start date

1989-01-01

Completion date

2012-12-31

Last updated

2024-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type2 Diabetes

Keywords

Fish, Polyunsaturated fatty acids, CHNS

Brief summary

The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of type 2 diabetes (T2D) is heavily debated but evidence from large populations in China is scant. The investigators aim to use data from the China Health and Nutrition Survey (CHNS) to assess the long-term association between fish, PUFA intake and T2D risk.

Detailed description

The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of T2D is heavily debated but evidence from large populations in China is still lacking. The investigators aim to utilize data from China Health and Nutrition Survey (CHNS, 1997-2011). The investigators will calculate cumulative means of fish and PUFA intake based on 3-day food records in each wave. Sex-specific Cox regression models will be used to estimate relative risk of T2D. Results from this work will provide epidemiological evidence for improving recommendations on fish and PUFA intake for Chinese in dietary guidelines.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Adults aged ≥20 with complete data on diet and follow-up time

Exclusion criteria

* Missing information for Type 2 diabetes * Type 2 diabetes * Cardiovascular disease

Design outcomes

Primary

Measure	Time frame	Description
Type 2 diabetes	From entry into the study (baseline: 1997-2009) until 2011	Incidence of type 2 diabetes, on basis of self-reported physician diagnosis, fasting plasma glucose ≥ 7.0 mmol/l or HbA1c ≥ 6.5%

Secondary

Measure	Time frame	Description
Fish and polyunsaturated fatty acids intake	From entry into the study (baseline: 1997-2009) until 2011	Cumulative averages of fish and PUFA intake based on 3-day 24-hr recall in each wave

Outcome results