Sarcoidosis
Conditions
Brief summary
Evaluation of the rate of achievement of serum protein electrophoresis (PPE) in diagnosis in a retrospective cohort of patients at Rennes University Hospital
Detailed description
In 50% of cases, sarcoidosis is associated with polyclonal hypergammaglobulinemia. The other forms have a normal gamma globulin level. The level of gamma globulinemia has not yet been studied as an evolutionary predictive factor. Furthermore, there are disseminated granulomatoses sharing common characteristics with sarcoidosis, associated with Common Variable Immunodeficiency deficit (DICV) type Primary Immunodeficiency syndrome (DIP), thus occurring in hypogammaglobulinemic patients.
Interventions
BIOLOGICALAnalysis of gamma globulin
Electrophoresis of proteins
Sponsors
Rennes University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
\- Patients newly diagnosed with sarcoidosis
Exclusion criteria
* Comorbidity responsible for a change in the level of gamma globulin * Other etiology of granulomatosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Study of gamma globulin level present in the blood at the time of diagnosis of sarcoidosis on disease activity | Day 1 | Electrophoresis rates of serum proteins |
| Study of gamma globulin level present in the blood at the time of diagnosis of sarcoidosis on the course of the disease | Day 1 | Electrophoresis rates of serum proteins |
Countries
France
Outcome results
None listed