Spermatocele
Conditions
Keywords
sperm motility, Clinical Trial , DA-9401
Brief summary
This study was conducted to investigate the effects of daily supplementation of Allium cepa L. and Cuscuta chinensis Lam. Extract Mixtures (DA-9401) on improvement of sperm motility.
Detailed description
This study was a 12 weeks, multi-center, randomized, double-blind, placebo-controlled human trial. Twenty subjects were randomly divided into Allium cepa L. and Cuscuta chinensis Lam. Extract Mixtures (DA-9401) or a placebo group. sperm motility profiles before and after the intervention.
Interventions
DIETARY_SUPPLEMENTDA-9401
DIETARY_SUPPLEMENTPlacebo
Placebo for 12 weeks.
Sponsors
Korean Society for Sexual Medicine and Andrology
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
MALE
Age
20 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 20-55 years * sperm motility 40\ 69%
Exclusion criteria
* History of alcohol or substance abuse * Participation in any other clinical trials within past 1 months * intense constipation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes of Sperm motility | 12 weeks | Changes of sperm profile were assessed before and after the intervention |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes of Sperm count | 12 weeks | Changes of Sperm count(X10\^6(M)/ml) profile were assessed before and after the intervention |
| Changes of Ejaculated volume | 12 weeks | Changes of Ejaculated volume(ml) profile were assessed before and after the intervention |
| Changes of Sperm morphology | 12 weeks | Changes of Sperm morphology(%) profile were assessed before and after the intervention |
| Changes of Ejaculated pH | 12 weeks | Changes of Ejaculated pH profile were assessed before and after the intervention |
| Changes of IIEF(International Index of Erectile Function) | 12 weeks | Changes of questionnaire profile were assessed before and after the intervention |
| Changes of MFS(Multidimensional Fatigue Scale) | 12 weeks | Changes of questionnaire profile were assessed before and after the intervention |
| Changes of hormone(Total testosterone, FSH, LH) | 12 weeks | Changes of hormone{Total testosterone(ng/ml), FSH and LH(mlU/ml)} profile were assessed before and after the intervention |
Countries
South Korea
Outcome results
None listed