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Normal Parameters of Cranial Vessels Using Cranial Vascular Duplex Among Egyptian Population

Standardization of Normal Parameters of Cranial Vessels by Using Extra and Trans Cranial Vascular Duplex Among Egyptian Population

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03252652
Enrollment
100
Registered
2017-08-17
Start date
2017-10-31
Completion date
2019-10-31
Last updated
2017-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atheroma; Carotid Artery, Atheroma; Cerebral, Atheroma of Cerebral Arteries, Atherosclerosis

Keywords

Cranial vessels, Normal parameters, Carotid Duplex, Egyptian

Brief summary

the study will be carried out to standardize normal parameters of vascular duplex ultrasound of the cranial vessels in the Egyptian population.

Detailed description

Atherosclerosis is a major cause of ischemic stroke and a significant proportion of strokes are thromboembolic in nature, arising from atherosclerotic plaques. Several studies have reported racial differences in the severity and distribution of carotid atherosclerosis. In the United States and Western communities, Extra-cranial carotid artery disease was estimated to be responsible for 20-30% of strokes. Little is known about the prevalence and distribution of carotid disease among the populations in the developing countries. Vascular duplex ultrasound is a useful, cheap and available diagnostic tool for assessing cranial vascular disease. Duplex ultrasound can be highly reliable with proper technique, without the risk of radiation in other imaging modalities, is well tolerated by all patients including those who are claustrophobic in MRI machines, and has much less risks compared to conventional angiography studies. Although vascular duplex has been used for years yet there is little researches had been done on normal population in the developing countries to collect results and compare it to the parameters that was collected and reviewed in the western developed populations. The parameters that would be used in this study include both the data collected by static and dynamic duplex scan which are the intimal-medial thickness, the vessels' diameter, peak flow velocity and peak flow volume both systolic and diastolic for either extra- or intra-cranial vessels.

Interventions

RADIATIONvascular duplex ultrasound imaging

Duplex ultrasound is a non-invasive evaluation of blood flow through cranial arteries and veins.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Normal subjects between 20-40 years

Exclusion criteria

* Diabetic patients, hypertensive patients, any evidence of vascular disease either peripheral or central, subjects refusing to participate

Design outcomes

Primary

MeasureTime frameDescription
Normal intimal-medial thickness measured in millimeter24 monthsEstimation of the intimal-medial thickness for cranial vessels.
Normal vessels' diameter measured in millimeter24 monthsEstimation of the vessels' diameter
Normal peak flow velocity measured in cm/sec24 monthspeak flow velocity both systolic and diastolic for cranial vessels
Normal indices24 monthspulsatility index and resistance index for cranial vessels

Secondary

MeasureTime frameDescription
Early detection of subjects at risk of atherosclerosis24 monthsdetection of subjects with early atherosclerotic changes for further management

Contacts

Primary ContactTarek A Rageh, PHD
Tarek_rageh@hotmail.com+0201223849203
Backup ContactKhaled O Abosheira, PHD
+0201003012229

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026