Gingiva Atrophy, Gingivitis
Conditions
Keywords
gingiva, keratinized mucosa, gingival graft
Brief summary
The present split-mouth controlled randomized clinical trial aimed to evaluate clinical and histological results of acellular dermal matrix allograft (ADM) compared to autogenous free gingival graft (FGG)
Interventions
PROCEDUREControl
Free epithelized gingival graft, harvested from palate, was grafted in a site with lack of keratinized gingiva
DEVICEAcellular Dermal Matrix
Acellular Dermal Matrix was grafted in a site with lack of keratinized gingiva, in substitution of an autogenous graft from patient palate
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
All clinical parameters were evaluated by a calibrated examiner (intraclass correlation coefficient = 0.98) blind to test and control groups.
Intervention model description
Split-mouth design. One side of mouth was test group, other side was control group.
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* absence or deficiency of keratinized tissue (\< 1mm) in two homologous contralateral sites of inferior premolars * Miller Class I or II gingival recession * Absence of radiographic bone loss * Vital tooth or with adequate endodontic treatment * Root surfaces without caries * Good oral hygiene (plaque index \< 20%)
Exclusion criteria
* Allergic to penicillin * Presenting systemic disease that impede surgical procedure * Smokers * Pregnancy * Intake of calcium channel blockers that cause gingival augmentation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| keratinized tissue width | 18 years | Distance from gingival margin to mucogingival junction, measured with a periodontal probe in mm. Ideal if mucosa width is \> 5mm. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Probing depth | 18 years | Distance from gingival margin to bottom of gingival sulcus, measured with a periodontal probe. Ideal if \< 2mm. |
| Attachment level | 18 years | Distance from cemento-enamel junction to bottom of gingival sulcus, measured with a periodontal probe. Ideal if \< 2mm. |
| Recession depth | 18 years | Distance from cemento-enamel junction to gingival margin, measured with a periodontal probe. Ideal if = 0mm. |
Countries
Brazil
Outcome results
None listed