Diabetes Mellitus, Exercise
Conditions
Brief summary
In this research work, the concept of strengthening technique of proprioceptive neuromuscular facilitation (PNF) incorporated with tendon gliding exercise (TGE) will be used to improve neuromuscular function of upper extremity of patients with diabetes mellitus. The first specific aim of the study is to examine the effects of home-based PNF exercise on the motor, sensation and functional performance parameters of upper extremity of the patients with diabetes mellitus. In addition, whether adding a tendon gliding exercise (TGE) to the home-based PNF exercises can provide better treatment effects for the patients with diabetes mellitus will also been investigated in this study. One of the hypothesis of this study is the prescribing home-based PNF exercise program has a positive treatment effect on neuromuscular function of the upper extremity of patients with diabetes mellitus. And,the other is home-based PNF in conjunction with TGE provides better benefits for neuromuscular function of the upper extremity of patients with diabetes mellitus.
Interventions
BEHAVIORALlifestyle changes
Providing a home-based exercise program supervised by therapists can be an acceptable strategy with the characteristics of convenience and inexpensiveness to promote neuromuscular and functional component for the patients with diabetes mellitus.
Sponsors
National Cheng-Kung University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Study participants will include clinically defined diabetic patients who are diagnosed based on the 1997 criteria of the American Diabetes Association. The inclusion criteria of the enrolled subjects are who suffered from neuropathy as diagnosed by abnormalities in either a nerve conduction study and / or quantitative sensory testing.
Exclusion criteria
* DM patients with (1) traumatic nerve injuries of the upper limbs, (2) trauma to the hand or congenital anomalies of the wrist and hand, (3) skin infections or disease, (4) known vascular complications of diabetes, such as stroke may have compromised the physical integrity of the patient, (5) grade 2 or higher arterial hypertension (\>160/100 mmHg) or (6) cognitive deficits
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline result of Semmes-Weinstein monofilament (SWM) test at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | determine the touch-pressure threshold of the hands |
| Change from baseline result of Nerve conduction study (NCS) at 12 weeks | pre-intervention (week 0) and follow-up evaluation (week 24) | determine nerve condition through detection of the amplitude of the sensory and motor nerve action potential |
| Change from baseline result of pinch-holding-up activity test at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | sensorimotor control of a hand |
| Change from baseline result of Purdue pegboard test at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | determine fine fingertip dexterity |
| Change from baseline result of Minnesota Manual Dexterity Test at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | determine unilateral and bilateral gross motor coordination of upper extremity |
| Change from baseline result of Manual tactile test at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | determine active touching sensation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline result of Grasp and pinch power at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | Grip strength of the hands will be assessed with a Jamar dynamometer |
| Change from baseline result of peak torque of shoulder internal rotation assessing by Bi-planar isokinetic dynamometer (BID) at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | Peak torque (PT) of shoulder internal rotation (N⋅m) will be obtained |
| Change from baseline result of pinch power at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | Pinch power is measured with a pinch gauge |
| Change from baseline result of of shoulder flexion assessing by Micro FET hand-held dynamometer at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | Peak force of shoulder flexion (N) will be measured |
| Change from baseline result of shoulder internal rotation assessing by Micro FET hand-held dynamometer at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | Peak force of shoulder internal rotation (N) will be measured |
| Change from baseline result of shoulder external rotation assessing by Micro FET hand-held dynamometer at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | Peak force of shoulder external rotation (N) will be measured |
| Change from baseline result of peak torque of shoulder external rotation assessing by Bi-planar isokinetic dynamometer (BID) at 12 weeks | pre-intervention (week 0), post-intervention (week 12) and follow-up evaluation (week 24) | Peak torque of shoulder external rotation (N⋅m) will be obtained |
Countries
Taiwan
Outcome results
None listed