Depression, Epilepsy
Conditions
Keywords
epilepsy, depression, drug treatment
Brief summary
The aim of this study is to register the drug treatment of depression in patients with epilepsy in East China.
Detailed description
As the treatment rate for depression in epilepsy is unclear and the discordant voice of choosing antidepressants for most doctors, this prospective observational cohort study was designed to better understand the current situation of drug treatments in patients with the comorbidity of epilepsy and depression in East China. The secondary outcome was to investigate whether baseline depressive symptoms had an influence on seizure-control in patients with epilepsy at follow-up.
Interventions
None listed
Sponsors
Shanghai Zhongshan Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
The inclusion criteria were as follows: (1) age 18-75, no gender limited; (2) diagnosis of epilepsy according to the definition by ILAE in 2014; (3) the score of 17-item Hamilton Depression Rating Scale greater than 7; (4) Obtaining informed consent of participants. The
Exclusion criteria
were any of the following: (1) having psychiatric symptoms such as hallucination or delusion; (2) progressive neurological diseases and malignant tumors; (3) severe cognitive dysfunction (the score of MMSE less than 10).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the drug treatment rate of depression in patients with epilepsy | 6 months | the drug treatment rate at baseline and 6 months at follow-up |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the influence of depression on seizure-control | 6 months | whether depression at baseline affects seizure-control 6 months later |
Countries
China
Contacts
Primary ContactWeifeng Peng, MD
Outcome results
None listed