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Predictive Factors and Complications of Delirium

Incidence, Predictive Factors and Complications of Delirium in Postoperative Cardiac Surgery Elderly Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03246165
Enrollment
173
Registered
2017-08-11
Start date
2011-09-01
Completion date
2015-06-30
Last updated
2019-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Age Problem, Delirium, Surgery--Complications

Brief summary

The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

Detailed description

Delirium is a transient and fluctuating course syndrome of acute onset that is characterized by reduced level of consciousness, global cognitive dysfunction, and disorder in the sleep-wake cycle. In patients undergoing cardiac surgery, delirium is a complication that affects 2-57% of the patients, reaching as high as 73% in older subjects. The identification of patients at high risk for delirium is important to deliver proper care and avoid the consequences of this complication. However, previous studies published on the subject have not delivered definitive results in the cardiac surgery setting. Low educational level has also been studied as a risk factor for delirium after surgery but never in a group of cardiac surgery patients that includes a significant rate of illiteracy. The objective of this research was to determine the incidence, predisposing and triggering factors of delirium following cardiac surgery and its consequences within 30 days of surgery and during a 12-18-month follow-up in older adult patients.

Interventions

PROCEDURECardiac surgery

Coronary bypass, heart valve replacement

Sponsors

Hospital de Messejana
CollaboratorUNKNOWN
University of Sao Paulo
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Elective cardiovascular surgery

Exclusion criteria

* Blindness, * deafness, * previous stroke * dementia * delirium at inclusion, preoperatively * creatinine clearance \< 30 ml/min * emergency surgery

Design outcomes

Primary

MeasureTime frameDescription
DeliriumUntil hospital discharge or 30 days after surgery, and for up to 18 months.Delirium was assessed using the Confusion Assessment Method for the Intensive Care Unit

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026