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The Effect of Blood Transfusion on Venoarterial PCO2 Difference in Cardiac Surgery

The Effect of Blood Transfusion on Venoarterial PCO2 Difference in Cardiac Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03245502
Enrollment
127
Registered
2017-08-10
Start date
2017-08-20
Completion date
2017-12-01
Last updated
2017-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Procedure Complication

Keywords

tissue oxygenation

Brief summary

Venoarterial CO2 difference(delta PCO2), lactate, central venous oxygen saturation(ScVO2) will be recorded in several steps in coronary artery bypass graft and valvular cardiac operations. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

Detailed description

Preoperative creatinine values, demographic data, comorbidities will be recorded in ASA I-II elective coronary artery and valvular cardiac surgery patients. Intraoperative delta PCO2, lactate, ScVO2 will be recorded in several steps. The patients will be divided into two groups as Transfused, and Non-Transfused Groups observationally. The trend of delta CO2, lactate, ScVO2, postoperative creatinine values, postoperative complications and 28 days mortality will be compared.

Interventions

BIOLOGICALBlood transfusion

The transfusion of erythrocyte suspension

Sponsors

Turkiye Yuksek Ihtisas Education and Research Hospital
Lead SponsorOTHER_GOV

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years

Inclusion criteria

* Elective cardiac surgery, stable cardiac function

Exclusion criteria

* Clinical signs of heart failure, symptomatic cerebral or peripheral failure, uncontrolled diabetes mellitus

Design outcomes

Primary

MeasureTime frameDescription
Complication5 daysThe postoperative neurologic, renal, hepatic, respiratory complications

Secondary

MeasureTime frameDescription
Mortality28 daysmortality

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026