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Physiological Effects of High-Flow Tracheal Oxygen Via An Modified Interface

Physiological Effects of High-Flow Tracheal Oxygen Via An Modified Interface in Tracheostomized Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03244761
Enrollment
20
Registered
2017-08-10
Start date
2017-07-01
Completion date
2018-02-05
Last updated
2018-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tracheostomy

Keywords

high flow tracheal oxygen, modified interface

Brief summary

Tracheostomy is often performed in patients after or anticipated prolonged mechanical ventilation, who are usually required oxygen therapy after discontinuation of mechanical ventilation.

Detailed description

Tracheostomy is often performed in patients after or anticipated prolonged mechanical ventilation, who are usually required oxygen therapy after discontinuation of mechanical ventilation.The high-flow tracheal (HFT) oxygen therapy in tracheostomized patients has been shown that can improve oxygenation,but can not induce positive end-expiratory pressure and elevation of end-expiratory lung volume. A modified HFT system by increasing expiratory resistance might induce PEEP and consequently elevate EELV.

Interventions

PROCEDUREThe modified HFT

The HFT was modified by increasing the expiratory resistance.

Sponsors

Capital Medical University
Lead SponsorOTHER

Study design

Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years

Inclusion criteria

* The tracheostomized patient requiring the convenient oxygen therapy.

Exclusion criteria

* Under 18 years; * history of esophageal, gastric or lung surgery; * The contraindication of using EIT (pacemaker, defibrillator, and implantable pumps).

Design outcomes

Primary

MeasureTime frameDescription
The mean end expiratory pressure.the last 1 minutes of steady breathing during the standard or modified HFT.The patients was delivering the high flow oxygen via the standard and modified HFT interface for 20 minutes.

Secondary

MeasureTime frameDescription
Changes in global and regional EELVthe last 1 minutes of steady breathing during the standard or modified HFT.The Electrical impedance tomography (EIT) was applied in monitoring the change of EELV at the bedside.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026