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Amiodarone Usage After Ischemic Ventricular Tachycardia Ablation

Effect of Amiodarone After Ischemic Ventricular Tachycardia Ablation

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03244748
Enrollment
100
Registered
2017-08-09
Start date
2016-01-01
Completion date
2018-03-01
Last updated
2017-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Cardiomyopathy, Ventricular Tachycardia, ICD Shock

Brief summary

Ventricular Tachycardia ablation in ischemic cardiomyopathy patients is required procedure in cases when anti-arrhythmic drugs failed. The concern is if adjunctive continuation amiodarone after ablation is needed.

Detailed description

Ischemic cardiomyopathy patients have implantable cardioverter defibrillators (ICD) to prevent arrhythmic deaths. Ventricular tachycardia (VT) events with frequent ICD interventions in ischemic cardiomyopathy patients is encountered frequently. Frequents ICD interventions is associated with worse outcomes. Anti-arrhythmic drugs ,mostly amiodarone, are given prevent ventricular arrhythmias and ICD interventions that may not be curative. Ablation of ventricular tachycardia is the suggested treatment when anti-drugs are without effect. After ablation of ventricular arrhythmia the continuation of amiodarone is not well elucidated. In this study we aimed to enroll ischemic cardiomyopathy patients having frequent ICD interventions despite medical treatment. VT ablation is performed and patients divided into two groups; group one continues having amiodarone after ablation, group two does not have amiodarone after ablation. Both groups will be compared in terms of recurrence and death.

Interventions

Electrophysiologic procedure aims to ablate and terminate arrhythmia percutaneously

Sponsors

Yuksek Ihtisas Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Ischemic cardiomyopathy patients applied with frequent ICD interventionor electrical storms and having ejection fraction below 50%. Frequent ICD defined as more than 1 ICD intervention within month. Electrical storm defined as more than 2 ICD intervention within one day.

Exclusion criteria

Patients with cardiomyopathies other than ischemic etiology

Design outcomes

Primary

MeasureTime frameDescription
Major adverse cardiovascular eventssix monthsDeath, ICD intervetion

Countries

Turkey (Türkiye)

Contacts

Primary ContactFirat Ozcan, Ass. Prof, MD
drfozcan@gmail.com+905327854000

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026