Skip to content

Skin Sympathetic Nerve Activity and Sympathetic Tone

Using Skin Sympathetic Nerve Activity to Estimate Sympathetic Tone in Human

Status
Enrolling by invitation
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03243448
Enrollment
1000
Registered
2017-08-09
Start date
2016-08-01
Completion date
2032-07-31
Last updated
2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy, Nerve; Disorder, Sympathetic

Brief summary

There are many sympathetic hyperactivity diseases in the investigators' clinical practice. However, the conventional method to measure the sympathetic nerve activity had many limitations such as clinical application, data interpretation and even therapeutic manipulation. Therefore the investigators would like to develop a non-invasive method to record the sympathetic nerve activity in the investigators' study that can help gathering the sympathetic nerve activity easily in the investigators' daily clinical situation. By the determination of sympathetic nerve activity status, the health caregiver can understand the disease more.

Interventions

None listed

Sponsors

Kaohsiung Medical University Chung-Ho Memorial Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 85 Years
Healthy volunteers
Yes

Inclusion criteria

* Sympathetic hyperactivity diseases included: hypertension, heart failure atherosclerotic diseases, arrhythmias, cardiomyopathy, pulmonary hypertension, chronic obstructive pulmonary disease, sleep apnea, pulmonary embolism, hepatitis, liver cirrhosis, hepatopulmonary syndrome, hepatorenal syndrome, renal failure, nephritis, irritable bowel syndrome. * Healthy Volunteers

Exclusion criteria

* Pregnant

Design outcomes

Primary

MeasureTime frameDescription
Skin Sympathetic Nerve Activity12 hoursThe Sympathetic Nerve Activity Recording from the skin of the subjects in the day time.

Secondary

MeasureTime frameDescription
ventricular arrhythmia24 to 72 hoursThe electrocardiogram recording from the telemetry.
Mortality1 to 12 monthsThe mortality will be accessed by the chart review and telephone access
Morbidity1 to 12 monthsThe morbidity will be accessed by the chart review and telephone access

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 11, 2026