Analysis, Event History, Blood, Point-of-Care Systems
Conditions
Brief summary
The aim of the present study is to quantify the time advantage achieved by the use of POCT compared to conventional coagulation diagnostics. A further objective of this study is an analysis of the result quality of POCT for the prothrombin time / international normalized ratio.
Detailed description
In order to be able to carry out a targeted coagulation therapy for the time-critical treatment of coagulopathic emergency patients, knowledge of the hemostatic potential is necessary. After taking blood samples for coagulation diagnostics, they are sent to the central laboratory. After the analysis and validation the electronic provision of the results takes place. The loss of time by sample transport, analysis and breadth of the results extends the duration until therapy can be started. The period of time until these analysis results are determined depends on several factors like daytime, day of week and location of the sample consignor and the availability of the laboratory. Not every clinic is connected to an internal tube mail system so that the samples have to be sent partly with a transport service. In recent years, Point of Care (POCT) devices have become an increasingly important tool for diagnosing coagulopathic patients.
Interventions
DIAGNOSTIC_TESTPOCT and central laboratory blood analysis
In every participant blood analysis will be performed by POCT and central laboratory investigating the time advantage.
Sponsors
Johann Wolfgang Goethe University Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age \> 18 years
Exclusion criteria
* Missing written consent * Withdrawal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time advantage | 2-4 hours | Duration until laboratory results are available after sampling for central laboratory versus POCT |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between central laboratory and POCT results. | 2-4 hours | Correlation of prothrombin time / international normalized ratio results between POCT and central laboratory analysis. |
| Influence of transport type. | 2-4 hours | Difference of results availability weather probes are transported by transport service or tube-mail. |
| Influence of daytime and weekday on results availability. | 2-4 hours | Difference of results availability in dependence of daytime and weekday on transport duration. |
Countries
Germany
Outcome results
None listed