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Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole

Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03241472
Enrollment
100
Registered
2017-08-07
Start date
2016-02-29
Completion date
2017-06-30
Last updated
2017-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

Infertility is defined as a couple's inability to become pregnant after one year of unprotected intercourse in women 35 years old and younger, and for six months in women over age 35 years. In any given year, about 15 percent of couples in North America and Europe who are trying to conceive are infertile

Interventions

DRUGLetrozole

oral tablets 5 mg

DRUGClomiphene Citrate plus N acetyl cystine

Clomiphene Citrate 100 mg oral tablets+ N acetyl cystiene 600 mg

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* All primary and secondary. Infertility due to anovulation

Exclusion criteria

* Male factor infertility, tubal factor. * Endocrineopathy * Hypothyrodism * Morbid obesity * Under weight * Patient with previous surgery including drilling of ovary, Clomiphene Citrate resistant to ovulation.

Design outcomes

Primary

MeasureTime frameDescription
rate of ovulation3 monthsultrasound evaluation

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 20, 2026