Obsessive-Compulsive Disorder
Conditions
Brief summary
A small (N = 24) pilot study developed a new and brief cognitive-behavioural therapy (CBT) module for checking symptoms (CBT-C) in obsessive-compulsive disorder (OCD). CBT-C targets maladaptive beliefs about memory and results show that it is effective at significantly decreasing checking symptoms as compared to a waitlist control. The objectives of the current investigation are to further investigate CBT-C by (1) replicating the pilot results in a larger sample; (2) using an active control condition (treatment as usual) as the comparison condition (3) including a 6-month follow-up, and (4) determining whether the association between maladaptive beliefs about memory at pre-treatment assessment are related to degree of checking symptom reduction following CBT-C. The findings of the study will have theoretical significance in adding to our understanding of the maladaptive belief domains relevant to the development and maintenance of OCD and supporting the cognitive model of compulsive checking. The relevant clinical significance is the further development of an intervention that could improve outcomes in treatment of persons with OCD. The key practical outcome of the research would be to add a stepped care offering to patients with OCD.
Interventions
BEHAVIORALCBT for Maladaptive Beliefs about Memory
The novel intervention is a manualized 2-session cognitive behavioural therapy. Agenda elements, including psycho-education, discussion prompts, and homework exercises are standardized across participants. In session 1, participants are taught about the cognitive theory of checking, the research support behind this theory, and how it may apply to their own checking behavior. A homework exercise is introduced and practiced to test out this theory. In session 2, the homework results are reviewed. Further education is shared on the nature of memory and the relationship to checking, and a discussion regarding how this applies to the participant's checking then takes place. A second homework exercise is introduced to test this theory.
OTHERTreatment as Usual
Treatment as Usual (TAU) during patients' time on our waitlist in our clinic will depend on at what point they have been recruited. It may consist of a 2-session group psychoeducational intervention on anxiety, any medications prescribed by their referring physicians, and/or independent therapy/counseling they may be seeking on the side. TAU for community participants will include any treatments they are currently seeking. Information about participation in such interventions will be collected during the course of the study (at each assessment visit) in order to accurately characterize participants' TAU in the current study.
Sponsors
University of Manitoba
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult over the age of 18 living in the province of Manitoba, Canada. * Diagnosis of OCD with clinically significant levels of compulsive checking (i.e., able to meet the diagnostic criteria for OCD according to the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition based solely on checking symptoms. Other OCD symptoms may be present and checking does not need to be the primary symptom.)
Exclusion criteria
* Active psychosis * Active Mania * Presence of a substance use disorder that would interfere with participation in the treatment
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vancouver Obsessional Compulsive Inventory - checking subscale (change) | Change in checking symptoms from pre-treatment to post-treatment at 3 weeks later | This six-item subscale of a self-report questionnaire measure assesses severity of checking-related OCD symptoms. |
| Average time spent checking per week (change) | Change in average time spent checking from pre-treatment to post-treatment at 3 weeks later | Participants record their daily time spent checking in daily diary records while in the active phase of the study. |
| Vancouver Obsessional Compulsive Inventory - checking subscale | Avarege time spent checking at 6-month follow-up | This six-item subscale of a self-report questionnaire measure assesses severity of checking-related OCD symptoms. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Beliefs about Memory Inventory (change) | Change in beliefs about memory from pre-treatment to post-treatment at 3 weeks later | Self-report questionnaire that assesses extent participant believes they have a bad memory. |
| Beliefs about Memory Inventory | Beliefs about memory at 6 month follow-up | Self-report questionnaire that assesses extent participant believes they have a bad memory. |
| Obsessive Beliefs Questionnaire (change) | Change in obsessive beliefs from pre-treatment to post-treatment at 3 weeks later | Self-report questionnaire that assesses maladaptive belief domains known to be related to checking. The responsibility/threat subscale is of particular interest as it is known to be related to checking behaviour. |
| Obsessive Beliefs Questionnaire | Obsessive beliefs at 6-month follow-up | Self-report questionnaire that assesses maladaptive belief domains known to be related to checking. The responsibility/threat subscale is of particular interest as it is known to be related to checking behaviour. |
Countries
Canada
Outcome results
None listed