Skip to content

Analgesic Effect of Adductor Canal Block With and Without Dexamethasone for Knee Arthroscopy

The Effect of Adding Dexamethasone to Bupivacaine in Ultrasound Guided Adductor Canal Block for Postoperative Analgesia Following Knee Arthroscopic Anterior Cruciate Ligament Reconstruction

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03239314
Enrollment
60
Registered
2017-08-04
Start date
2016-10-31
Completion date
2017-07-22
Last updated
2017-08-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Analgesia

Brief summary

The purpose of this study was to evaluate the efficacy of ultra-sound guided adductor canal block with and without dexamethasone when added to bupivacaine on the duration of postoperative analgesia in patients undergoing arthroscopic anterior cruciate ligament reconstruction surgery using Numeric Rating Score (NRS).

Detailed description

Adductor canal block was done by Ultra-sound. After confirmation of the block and exclusion of any signs of toxicity or nerve injury, the patients operations were done under spinal anesthesia. Patients were allocated into one of 2 groups (30 patients per group). I. Group I: the patients received a single-shot of 20 ml plain bupivacaine (0.5%) +2 ml normal saline. ii.Group II: the patients received 20ml plain bupivacaine (0.5%) + 8 mg dexamethasone (2ml). Postoperative pain were assessed by Numeric Rating Scale (N.R.S) every 6 h post-operatively for 24 h. Whenever, the NRS Score was ≥4 or the patient requested pain medication, analgesia was provided by ketorolac 30 mg amp IV, then morphine 1mg ̸ kg slowly IV as a rescue analgesia. Time to first request for analgesia & total dose of rescue analgesia were be recorded. 10\. Satisfaction score will be measured on a linear numerical scale; ranging from 0 = complete dissatisfaction to 10 = complete satisfaction. Any post-operative side effects, like nausea, vomiting, bradycardia, hypotension will be also documented. The time to first analgesic requirement will be recorded, and the cumulative, post-operative opioid consumption in 24 h post-operatively will be recorded. Assessment of Quadriceps Strength at preoperative, 6, 12, 18, and 24 h postoperative from zero to 5.

Interventions

DRUGSaline Solution

Injected in the adductor canal

DRUGDexamethasone

Injected in the adductor canal

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult ASA I-II Arthroscopic anterior cruciate ligament reconstruction

Exclusion criteria

* patient refusal * drug allergy * failed procedure

Design outcomes

Primary

MeasureTime frameDescription
duration of postoperative analgesiaOne day postoperativeassessed by pain score

Secondary

MeasureTime frameDescription
postoperative analgesic consumptionOne day postoperativepostoperative opioid consumption

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026