Unbound Bilirubin Levels in Healthy Term and Late Preterm Infants

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03237715

Enrollment

180

Registered

2017-08-02

Start date

2017-07-01

Completion date

2019-06-30

Last updated

2017-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal Jaundice

Brief summary

Specific Aim 1: To determine total serum bilirubin (TSB) and unbound bilirubin (Bf) levels in term and late preterm infants during the first week of life. Specific Aim 2: Measure Bf levels in breast fed and formula fed infants and examine their relationship to unbound fatty acid (FFAu) levels. Specific Aim 3: To demonstrate that phototherapy results in different changes in TSB and Bf.

Interventions

OTHERAssessment of unbound bilirubin levels

Collection of residual blood for measurement of unbound bilirubin

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

6 Hours to 7 Days

Inclusion criteria

* Term and late-preterm infants admitted to the regular care nursery of Robert Wood Johnson University Hospital will be eligible for the study

Exclusion criteria

* Infants suffering from genetic, chromosomal or surgical conditions will be excluded.

Design outcomes

Primary

Measure	Time frame
Unbound bilirubin levels in term and late preterm infants	Two years
Unbound bilirubin levels in breast-fed versus formula-fed term and late preterm infants	Two years
Effect of phototherapy on unbound bilirubin levels	Two years

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026