Ovarian Cancer
Conditions
Brief summary
Evaluation of surgical excision of cardiophrenic lymph nodes in patients with advanced ovarian cancer
Detailed description
The role of cardiophrenic lymph node assessment and excision in advanced ovarian cancer is still debatable , correlation of radiological finding with pathological findings after reaction of radiological positive lymph nodes and its impact in diseases free survival and over all survival
Interventions
PROCEDUREcardiophrenic lymph nodes resection
surgical resection
Sponsors
Mansoura University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Ovarian cancer patient (FIGO stage III-IV) * Preoperative CT showing CPLN with short axis diameter \> 5mm. * Anathestically fit patient (ASA score I or II). * Accepted pulmonary function test. * Patient who received neoadjuvant chemotherapy or recurrent cases may be enrolled * Written informed consent. * Achievement of optimal cytoreduction intra-abdominal( No residual disease more than 1 cm )
Exclusion criteria
* Anathestically unfit patient * Unresectable disease * Patient refusal * No detected CPLN by preoperative radiology
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| number of CPN retrieved/pathological nodes | up to 3 years | correlation of radiological active lymph nodes with pathological findings |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Progression free survival | up to 2 years following the end of study | 2 years progression without disease recurrence |
Other
| Measure | Time frame | Description |
|---|---|---|
| Overall survival | up to 2 years following the end of study | 2 years survivals of the patients |
Countries
Egypt
Contacts
Primary ContactBasel R. Abdelfattah, MD, MRCS
Outcome results
None listed