Coronary Artery Disease
Conditions
Brief summary
A single center cohort which enrolled women who performed mammography, bone densitometry (DEXA), and coronary CT angiography in Seoul National University Bundang Hospital from March 2011 to February 2013.
Detailed description
To evaluate whether bone mineral density and breast arterial calcification can predict coronary artery disease in women older than 40 years
Interventions
DIAGNOSTIC_TESTCoronary CT angiography
Presence of coronary plaques Characteristic of coronary plaques
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Women (≥ 40 years) who performed mammography, bone DEXA, and coronary CT angiography at health promotion center of Seoul National University Bundang Hospital.
Exclusion criteria
* Women who have history of breast surgery or intervention * Women who have history of myocardial infarction or revascularization * Too poor image quality of coronary CT angiography for interpretation * Renal dysfunction with serum creatinine ≥ 1.4mg/dL
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Presence of coronary plaque | 5 years | Any coronary plaque in coronary CT angiography |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Characteristics of coronary plaque | 5 years | Plaque characteristics (fibrosis, calcification, lipid, thrombosis) in coronary CT angiography |
| Major adverse cardiovascular events | 5 years | Cardiac death, nonfatal myocardial infarction, ischemic stroke, coronary revascularization |
Outcome results
None listed