Sedation
Conditions
Brief summary
comparison between propofol-fentanyl and propofol-ketamine for sedation in pediatric diagnostic gastrointestinal endoscopy.
Detailed description
It is a prospective double blinded controlled study that will be carried out on 60 pediatric patients undergoing GIT endoscopy; they will be divided into two groups of 30 patients each:- Group I (PF): will receive 0.5 µg/ kg fentanyl + 2 mg/ kg propofol IV. Group II (KF): will receive Ketofol (1 ketamine: 4 propofol) 0.5 mg/kg ketamine + 2 mg/kg propofol IV.
Interventions
DRUGFentanyl
fentanyl used with propofol for sedation
DRUGKetamine
ketamine used with propofol for sedation
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Masking description
double blind
Eligibility
Sex/Gender
ALL
Age
6 Years to 16 Years
Healthy volunteers
No
Inclusion criteria
* Pediatric patients undergoing diagnostic GIT endoscopy * ASA I-II
Exclusion criteria
* Emergency endoscopy * Respiratory infection and hyperactive airways * History of serious adverse effects related to anesthetics (e.g. allergic reactions), a family history of reactions to the study drugs * Morbid obesity, and neuropsychiatric disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidence of desaturation | up to 2 days after operation | when oxygen saturation below 90% |
Contacts
Primary ContactMohamed Aly
Outcome results
None listed