Intrathoracic Lymphadenopathy
Conditions
Brief summary
The study is aimed at verifying if a pulmonologist in training can reliably assess the adequacy of EBUS-TBNA samples from intrathoracic lymphadenopathy after a period of training provided by an experienced pathologist.
Interventions
DIAGNOSTIC_TESTRapid on-site evaluation
On-site (endoscopy suite) evaluation, by a pathologist or a pulmonologist, of specimens retrieved from intrathoracic lymph nodes during EBUS-TBNA
Sponsors
Maggiore Bellaria Hospital, Bologna
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Indication to sampling of intrathoracic lymphadenopathy based on computed tomography (CT) and/or positron emission tomography (PET)/CT findings * Signed informed consent
Exclusion criteria
* High risk conditions for the performance of bronchoscopy and endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) * High risk condition for deep sedation (ASA 4) * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy with which the pulmonologist will identify inadequate EBUS-TBNA samples | Up to 1 week | The Outcome 1 will be measured by verifying the agreement between the pulmonologist judgment and the pathologist judgment, the latter being the gold standard |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy with which the pulmonologist will be able, in case of adequate EBUS-TBNA sample, to assign the specimen to one of the following specific diagnoses: 1) reactive lymph node; 2) malignancy; 3) granulomatous inflammation | Up to 1 week | The Outcome 1 will be measured by verifying the agreement between the pulmonologist judgment and the pathologist judgment, the latter being the gold standard |
Countries
Italy
Outcome results
None listed