Effect of Mechanical Loading With PTH on Cortical Bone

Status

Withdrawn

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03232476

Enrollment

Registered

2017-07-28

Start date

2017-07-31

Completion date

2019-12-31

Last updated

2025-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis, Postmenopausal

Brief summary

Clinical trial to investigate effect of voluntary upper extremity loading in combination with anabolic osteoporosis therapy.

Interventions

DEVICEUpper extremity voluntary loading

Subjects who are prescribed teriparatide by their healthcare provider may enroll in this study. The study intervention consists of loading one upper extremity. Subjects will be trained on how to perform the upper extremity exercises at home. Subjects will be expected to perform the exercises 3 days per week using one arm, with each session consisting of 100 loading cycles lasting a total of approximately 2 minutes each day.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

45 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* women aged 45+ * postmenopausal * osteoporotic with high risk of fracture

Exclusion criteria

* no significant previous use of bone health modifying treatments

Design outcomes

Primary

Measure	Time frame
radius bone mineral density	12 month change

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026