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Ultrasound-guided Peripheral IJ Study

Ultrasound-guided Placement of Peripheral Intravenous Lines in the Internal Jugular Vein.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03231345
Enrollment
35
Registered
2017-07-27
Start date
2016-08-18
Completion date
2018-05-31
Last updated
2019-01-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IV Access

Keywords

Peripheral IV, Internal jugular vein, IJ, Peripheral IJ, Ultrasound-guided IJ

Brief summary

Difficult venous access in some patients such as those with obesity, IV drug use, chronic illness, or vascular pathology often causes increased discomfort and delayed patient care due to multiple attempts to gain venous access. If access is achieved at all, it usually results in a much smaller catheter than needed to provide optimal care for the patient. Ultrasound-guided placement of a peripheral IV in the internal jugular vein is common in the investigators' emergency department and is gaining popularity across the US. This study investigates the utility and safety of placing an ultrasound-guided peripheral IV catheter in the internal jugular vein.

Detailed description

Intravenous access in the emergency department (ED) patient is essential for medication delivery, IV fluid resuscitation, rapid serum laboratory diagnostics, and administration of IV contrast for CT scans. Some patients, such as those with obesity, IV drug abuse, chronic illnesses, or vascular pathology may have difficult IV access. These patients are problematic for the busy ED nurse and physician as this can lead to a time consuming process, which slows efficiency and patient care. Previously, patients with difficult IV access often required central venous catheterization, a procedure that can result in a number of serious complications (1). More recently, ultrasound guidance has been touted as an effective means to achieve peripheral IV access on these patients (2). In one study (2), there was a 73% first attempt cannulation rate, which seems respectable, but not excellent. Additionally, 8% of the successful IVs failed within one hour (2). Another study compared ultrasonographically guided peripheral IVs to non-ultrasonographically guided IVs, and it found that using ultrasound did not decrease the amount of time or the number of attempts it took to successfully place a peripheral IV (3). Although ultrasound-guided peripheral IV's have a role, there remains room for improvement in being able to achieve rapid IV access in those patients who need IV access on an urgent basis. It seems that we still have room to improve our ability to obtain difficult IV access, and a relatively new technique may be the answer. Ultrasound guided IVs are typically attempted in the upper extremities, targeting the brachial or basilic veins, but a recently described technique --- the peripheral IJ --- involves placement of a peripheral IV catheter in the internal jugular vein (4,5). The peripheral IJ is gaining popularity in the investigators' ED as a solution to the difficult vascular access patient. In the investigators' clinical experience, it is a quick and easy procedure that is also safe, tolerated well by patients, and requires few resources. Several small studies have concluded that this is a fast and safe procedure and a feasible alternative to central access in the difficult vascular access patient (4-7). These studies mention the theoretical risks as being similar to central venous access such as carotid artery puncture, hematoma, pneumothorax, and line infection, however none of these have actually been reported (4-7). Therefore, we seek primarily to determine the average number of attempts to cannulation for ultrasound-guided peripheral IJ placement. Secondarily, we wish to determine: 1) the prevalence of potential complications related to this procedure 2) the average time it takes the emergency physician to complete the procedure 3) the patient's satisfaction with the procedure. We will compare the data from this study to the published data for other types of ultrasound-guided peripheral IVs.

Interventions

PROCEDUREUS guided IJ

IV catheter placement

DEVICEUltrasound

Ultrasound-guided Internal Jugular vein

Sponsors

University Medical Center of Southern Nevada
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Intervention model description

This study utilizes a convenience sample of patient who have difficult venous access with at least 2 attempts by nursing to achieve venous access. The patient will be consented and a physician placed ultrasound-guided peripheral IV will be placed in the internal jugular vein.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* At least 2 unsuccessful attempts at peripheral IV access by ED nursing * Age 18 or older

Exclusion criteria

* Critically ill patients with clinical indications for emergent central venous access. * Overlying skin infection * External jugular vein easily visible for cannulation * Patient in law enforcement custody * Patient who is known to be pregnant or self identifies as pregnant * Patient lacking decision making capacity

Design outcomes

Primary

MeasureTime frameDescription
Number of Participants With Successful Cannulation of the Internal Jugular VeinLess than 20 minutesThe primary study endpoint is successful cannulation vs failure to cannulate the internal jugular vein.

Secondary

MeasureTime frameDescription
Prevalence of Complications Related to Cannulation of the Internal Jugular Vein.24 hoursPercentage of Participants with successfully placed lines with a complication
The Median Time Required for Cannulation of the Internal Jugular Vein by an Emergency Physician.Less than 20 minutesThe median time it took an Emergency Physician from needle puncture to cannulation in minutes

Countries

United States

Participant flow

Participants by arm

ArmCount
US Guided IJ
A physician placed ultrasound-guided IV in the internal jugular vein US guided IJ: IV catheter placement Ultrasound: Ultrasound-guided Internal Jugular vein
35
Total35

Baseline characteristics

CharacteristicUS Guided IJ
Age, Continuous48.2 years
STANDARD_DEVIATION 15.6
Race/Ethnicity, Customized
African American
14 Participants
Race/Ethnicity, Customized
Asian
1 Participants
Race/Ethnicity, Customized
Caucasian
14 Participants
Race/Ethnicity, Customized
Hispanic
6 Participants
Region of Enrollment
United States
35 Participants
Sex: Female, Male
Female
25 Participants
Sex: Female, Male
Male
10 Participants

Adverse events

Event typeEG000
affected / at risk
deaths
Total, all-cause mortality
0 / 35
other
Total, other adverse events
1 / 35
serious
Total, serious adverse events
0 / 35

Outcome results

Primary

Number of Participants With Successful Cannulation of the Internal Jugular Vein

The primary study endpoint is successful cannulation vs failure to cannulate the internal jugular vein.

Time frame: Less than 20 minutes

ArmMeasureValue (COUNT_OF_PARTICIPANTS)
US Guided IJNumber of Participants With Successful Cannulation of the Internal Jugular Vein34 Participants
Secondary

Prevalence of Complications Related to Cannulation of the Internal Jugular Vein.

Percentage of Participants with successfully placed lines with a complication

Time frame: 24 hours

ArmMeasureValue (COUNT_OF_PARTICIPANTS)
US Guided IJPrevalence of Complications Related to Cannulation of the Internal Jugular Vein.1 Participants
Secondary

The Median Time Required for Cannulation of the Internal Jugular Vein by an Emergency Physician.

The median time it took an Emergency Physician from needle puncture to cannulation in minutes

Time frame: Less than 20 minutes

ArmMeasureValue (MEDIAN)
US Guided IJThe Median Time Required for Cannulation of the Internal Jugular Vein by an Emergency Physician.3.1 minutes

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026