Pleural Effusion Drainage in Mechanically Ventilated Patients Monitored by EIT

Effects of the Pleural Effusion Drainage in Mechanically Ventilated Patients Monitored by Electrical Impedance Tomography and End-Expiratory Lung Volume

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03231072

Enrollment

Registered

2017-07-27

Start date

2017-01-31

Completion date

2022-03-30

Last updated

2022-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drainage, Electric Impedance Tomography, Pleural Effusion

Keywords

mechanical ventilation, pleural effusion, EIT

Brief summary

Evacuation of pleural effusion (PE) represents a disputable therapy in mechanically ventilated patients. Patients on mechanical ventilation indicated by the physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured in order to describe impact of PE evacuation on aeration and ventilation of the lungs.

Detailed description

Critically ill patients treated in intensive care units have a disorder of distribution and volume of body fluids due to principal illness and some therapeutic interventions. One of its manifestations is pleural effusion (PE) formation. Patients on mechanical ventilation indicated by treating physician to pleural fluid evacuation will be monitored throughout the procedure by electrical impedance tomography (EIT) and concurrently end-expiratory lung volume (EELV) will be measured. The purpose of the study is to better understand impact of PE evacuation on aeration and ventilation of the lungs.

Interventions

DEVICEElectrical Impedance Tomography record

Monitoring of pleural effusion evacuation by means of EIT

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* mechanical ventilation, presence of pleural effusion, decision of the treating physician to drain it

Exclusion criteria

* impossibility to apply EIT belt or to find suitable save point for drainage when the EIT belt is attached * standard EIT

Design outcomes

Primary

Measure	Time frame	Description
Change of the thorax electrical impedance following pleural effusion drainage in mechanically ventilated patients	4 hours	Comparison of EIT results with end-expiratory lung volume measurement during drainage of pleural effusion

Secondary

Measure	Time frame	Description
Change of the distribution of ventilation following pleural effusion drainage in mechanically ventilated patients	4 hours	Change of distribution of ventilation over EIT regions of interest (ROIs)

Countries

Czechia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026