Pulmonary Disease, Chronic Obstructive
Conditions
Brief summary
Chronic obstructive pulmonary disease is a common respiratory condition that is characterized by inflammation of the large and small peripheral airways , the alveoli and adjacent capillary networks. Severe airflow obstruction that imposes a significant load on the respiratory system is a major manifestation of Chronic obstructive pulmonary disease. The reduced expiratory airflow also causes air trapping at the end of expiration , producing alveolar pressure that are higher than atmospheric pressure before the next breath. This condition is intrinsic positive end-expiratory pressure .
Interventions
DEVICEMechanical ventilator
Mechanical ventilation, in the healthcare setting or home, helps patients breathe by assisting the inhalation of oxygen into the lungs and the exhalation of carbon dioxide. Depending on the patient's condition, mechanical ventilation can help support or completely control breathing.
Sponsors
Assiut University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* patient with acute exacerbation of Chronic obstructive pulmonary disease and respiratory failure who are intubated and mechanically ventilated.
Exclusion criteria
* patient with neuromuscular diseases. * patient with pulmonary vascular diseases e.g pulmonary embolism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The duration of mechanical ventilation | 1 month |
Countries
Egypt
Contacts
Primary ContactSuzan Salama, MSc
Backup ContactAliae Abd Rabou, MD
Outcome results
None listed