Follow Up Study for Treatment of Parkinson's Disease With Subthalamic Deep Brain Stimulation

Long Term Study of Subthalamic Deep Brain Stimulation for Parkinson's Disease

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03230331

Enrollment

Registered

2017-07-26

Start date

2017-07-24

Completion date

2019-05-01

Last updated

2020-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson Disease

Brief summary

This study aims to evaluate the long term effect of deep brain stimulation in the the subthalamic nucleus (STN) in patients with Parkinson's disease.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Inclusion criteria

* Idiopathic Parkinson's disease * Disease duration longer than 15 years * Had STN deep brain stimulation implant more than 10 years * Available and willing to be followed-up according to study protocol

Exclusion criteria

* Patients with serious diseases such as tumor, sever liver or kidney dysfunction were not selected in the clinical trials * Epilepsy * Pregnant female * History of severe neuropsychiatric disease * Patients are taking part in other clinical trials in recent several months

Design outcomes

Primary

Measure	Time frame
Changs in the score of Stand-Walk-Sit Test	above 10 years post surgery

Secondary

Measure	Time frame
UPDRS part I score	above 10 years post surgery
UPDRS part II score	above 10 years post surgery
UPDRS part IV score	above 10 years post surgery
39-Item Parkinson´s Disease Questionnaire (PDQ-39) score	above 10 years post surgery
Freezing of Gait Questionnaire (FOG-Q) score	above 10 years post surgery
Gait and Falls Questionnaire (GFQ) score	above 10 years post surgery
Change of the score in United Parkinson Disease Rating Scale (UPDRS) part III	above 10 years post surgery
Montreal Cognitive Assessment (MoCA) Beijing score Version	above 10 years post surgery
Frontal Assessment Battery (FAB) score	above 10 years post surgery
Hamilton Anxiety Scale (HAMA) score	above 10 years post surgery
Hamilton Depression Scale-17 (HAMD-17) score	above 10 years post surgery
Apathy Evaluation Scale score	above 10 years post surgery
Mini-Mental State Examination (MMSE) score	above 10 years post surgery

Countries

China

Outcome results