Neonatal Asphyxia
Conditions
Keywords
Neonatal asphyxia, neonatal acidosis, fetal ECG, umbilical cord acid-base status
Brief summary
This is an historic cohort study based on the birth and delivery register of the HFME maternity ward. This study aim at understanding the evolution of asphyxia at birth, at all gestational ages, identifying causes and describing neonatal outcomes since 2000, when a second line strategy for foetal surveillance (fetal ECG) and systematic umbilical acid-gas cord blood were introduced in our maternity ward. The investigator's hypothesis was that the neonatal asphyxia decrease could be due to 3 main factors including second line strategy introduction, systematic umbilical cord acid-base implementation and improvement in antenatal risk factor screening for asphyxia. The investigator's second hypothesis was that neonatal prognosis in neonates with acidosis was improved with systematic early after birth EEG evaluation, allowing early treatment and surveillance.
Interventions
None listed
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 1 Hours
Healthy volunteers
No
Inclusion criteria
* All births at the maternity ward of the hospital Femme-Mère-Enfant from 1st of january 2000 to 31 december 2016
Exclusion criteria
* Infants born after medical pregnancy termination and born out of the hospital and secondarily hospitalized in our department will be excluded
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Rate of Neonatal asphyxia | 2 months | Neonatal asphyxia define as fetal death, neonatal death, NICU transfer, neonatal seizure, umbilical-artery blood pH ≤ 7.05 with a base deficit ≥ 12 mmol per liter, intubation for ventilation at delivery or neonatal encephalopathy |
Countries
France
Outcome results
None listed