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Study on Communication Comprehension in the Schizophrenic Spectrum

Study on Communication Comprehension in the Schizophrenic Spectrum

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03225027
Acronym
SKYPROVERB
Enrollment
59
Registered
2017-07-21
Start date
2016-11-15
Completion date
2019-05-27
Last updated
2019-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia Simple

Keywords

Emotional prosody, schizophrenia

Brief summary

The purpose of the present study is to evaluate the effect of emotional prosody on the perception of emotional discourse in the schizophrenic spectrum. The investigators hypothesize that participant may use emotional prosody as an emotional cue to understand the emotional content of discourse.

Detailed description

The integration of ortholinguistic and paralinguistic functions in language, particularly of the emotional prosody, is necessary to interact adaptively with others. People in the schizophrenic spectrum have social difficulties. Is emotional prosody comprehension altered in these people? According to Edwards et al. (2002), there is methodological issues concerning the tasks used to answer this question. Investigators built an emotional judgment task more adapted to study the perception of emotional prosody in the schizophrenic spectrum than the classical paradigm designed to evaluate participants with cerebral injury. The investigators have elaborated a material that consists of 140 short sentences (7±2 words) with a simple syntactic structure. The verbal content expressed positive, neutral or negative emotions. These sentences were announced by four professional actors (two female) with an emotional prosody content congruent or inconsistent with the verbal content. Participants will have to evaluate the emotional intensity of the recordings on a five points Likert scale, from strongly negative to strongly positive. Psychotic experiences of all participants will be evaluated too.

Interventions

Evaluating the exclusion criteria in healthy participants.

BEHAVIORALEmotional judgment task

Participants had to indicate on a computer the emotional intensity of audio recordings.

BEHAVIORALPost-experimental questionnaire

Participants will be invited to give us the cognitive strategy used to resolve the emotional judgment task.

BEHAVIORALRecognition task

Participants will be invited to indicate which recordings they had heard during the emotional judgment task to verify that they have paid attention to the emotional task.

BEHAVIORALDetection task

Participants indicate every time they heard a given sound in order to verify their audition level.

OTHERCAPE-42

This questionnaire allows evaluating the nature of psychotic experiences.

DIAGNOSTIC_TESTTrait Emotional Intelligence Questionnaire

To evaluate their emotional intelligence.

DIAGNOSTIC_TESTPositive And Negative Syndrome Scale

Evaluating the clinical status of patients with schizophrenia.

Sponsors

Hôpital NOVO
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Intervention model description

One experimental procedure proposed to three groups of participants

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Having a diagnosis of schizophrenia and being in a stable phase of the disease * Having between 18 to 60 years old * Speak french or using french at school * Accepting not to use psychoactive substances during the preceding 48h * Being affiliated to the French social security * Providing their written informed consent Non-inclusion Criteria: * Having not audio deficits, nor visual uncorrected deficits * Having not suffering from depressive symptoms during the last 6 months

Exclusion criteria

\- Having no neurological, nor psychiatric disease except schizophrenia for the patients groups.

Design outcomes

Primary

MeasureTime frameDescription
Behavioural measures (response rate and time)During the experimentParticipants will have to judge the emotional intensity of audio recordings. In this task, the participant is asked to judge the emotional intensity of audio recordings of men and women (2 actors + 2 actresses): he / she must press a button as quickly as possible to indicate whether the Audio recordings presented via small speakers are very negative, negative, non-emotional, positive or very positive (5 possible choices). The response time variable may be added as a co-variable in order to avoid perceptive-motor disorders (medication-related and / or general motor slowdown) that may influence the results of time-of- answers.

Secondary

MeasureTime frameDescription
Symptomatic impactDuring the experimentEvaluate the nature of the psychotic experiments (CAPE-42 test).
Evaluate the cognitive functioningDuring the experimentNeuropsychological tests will allow evaluating the cognitive profile of the participants that can impact their behaviour during the experiment.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026