Disorders of Lipoprotein Metabolism and Other Lipidaemias
Conditions
Keywords
Lipoprotein and Apolipoproteins metabolism
Brief summary
Theranostic translation applications against viral, metabolic liver diseases and hepatic oncogenesis: lipoprotein and apolipoproteins at a crossroad
Detailed description
An intimate link between microbial infections, metabolic changes and oncogenesis has been drawn attentions increasingly, indicating a crossroad leading to pathogenesis and disease progression. Globally the burden of hepatitis B and C virus infections is 450 and 185 millions, respectively and chronic hepatitis disease causes a high risk of liver cirrhosis, hepatocellular carcinoma and metabolic disorders
Interventions
To find out the role of lipoprotein and apolipoproteins (apos) in pathogenic hepatic diseases
Sponsors
Study design
Eligibility
Inclusion criteria
1. above 20 years 2. nonalcoholic fatty liver disease 3. Non-Alcoholic Steatohepatitis
Exclusion criteria
1\. alcohonic hepatitis 2. Autoimmune liver disease 3. HIV postive \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Theranostic Translation Applications Against Viral, Metabolic Liver Diseases and Hepatic Oncogenesis: Lipoprotein and Apolipoproteins at a Crossroad | 2years | Study the interplay between hepatitis C virus (HCV) and lipid metabolism(the HCV infection affects host lipid homeostasis, regarding transportation, synthesis, and catabolism.) |
Countries
Taiwan