Predicting Dropout and Outcome From Neuropsychological Functions in SUD Patients

Predicting Early Treatment Termination (Dropout) and Post-treatment Clinical Outcome From Neuropsychological Functions in Abstinent Substance Use Dependent (SUD) Patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03220373

Enrollment

200

Registered

2017-07-18

Start date

2017-03-07

Completion date

2029-12-31

Last updated

2024-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Substance Use Disorder (SUD)

Keywords

Neuropsychology, Cognition, Drop-out, Follow-up

Brief summary

The aim of this project is to gain a more specific understanding of how different cognitive profiles predict residential treatment drop-out, treatment retention and post-treatment outcome in a population with Substance Use Disorder.

Detailed description

This project collects the neuropsychological profile of residential SUD patients, in addition to treatment length, exit reason, hospital journal data and post-treatment clinical outcome data. The project aims to identify clinically relevant neurocognitive domains that predict treatment dropout and post-treatment clinical outcome. This will make it possible for future clinicians to focus their effort on neurocognitive functions most relevant for this particular patient group. RESEARCH QUESTIONS: 1. What neurocognitive domain (and sub-domain) are the strongest predictor of treatment drop-out and retention? 2. What neurocognitive domain (and sub-domain) are the strongest predictor of post-treatment clinical outcome variables such as drug use, health and social integration. 3. Will data on treatment length, age, gender, substance abuse history or psychiatric co-morbidity predict outcome independently, or in interaction with, the neuropsychological profile? This longitudinal prospective cohort study aims for a continuous collection of neuropsychological data baseline and post-treatment follow-up data until 2030.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Inclusion criteria

* Substance Use Disorder (SUD) patients. * 18 years or older. * Qualified to consent to research participation. * Able to speak and write in Norwegian.

Exclusion criteria

* Not qualified to consent to research participation. * Insufficient understanding of Norwegian.

Design outcomes

Primary

Measure	Time frame	Description
Exit reason	On average 3 months	Reason for terminating residential SUD treatment (Treatment completed or Drop-out)
Treatment retention	On average 3 months	Number of days in treatment

Secondary

Measure	Time frame	Description
Quality of Life	1 year after neuropsychological assessment	QoL-5 (Quality of Life)
ADHD symptoms	1 year after neuropsychological assessment	ASRS (ADHD Self-Report Scale)
Substance use	1 year after neuropsychological assessment	DUDIT (Drug Use Disorders Identification Test)
Housing	1 year after neuropsychological assessment	Nature of present accommodation
Income	1 year after neuropsychological assessment	Nature of income
Psychological distress	1 year after neuropsychological assessment	SCL-10 (Symptom Checklist)

Countries

Norway

Outcome results