Formularies
Conditions
Keywords
Essential medicines lists
Brief summary
The World Health Organization (WHO) has developed a model list of more than 400 medicines and recommends that each country adapt the list to its own circumstances. More than 100 countries have developed essential medicines lists. Some countries have essential medicines lists that are very similar to the WHO's model list and other countries have lists that are very different from the WHO's model list. Differences between the WHO list and country lists could be explained by features of the country including population demographics, disease prevalence, Gross Domestic Product (GDP), and healthcare system organization. Other factors such as the influence of particular individuals or organizations may also explain differences between countries. The purpose of this project is to compare the essential medicines lists developed by countries with the WHO's model list and to identify attributes of countries that are associated with differences from the WHO list. Predictors such as region, population, life expectancy, infant mortality rate, GDP per capita, health expenditure per capita, inequality, and the corruption perception index will be considered.
Detailed description
Statistical analysis plan for objective 3 (relationship between the total number of differences and country features) Plots will be generated to show the relationships between variables. Correlation coefficients will be calculated where appropriate. Two separate multivariate models will be fit to the data for outcomes 2a and 2b \[continuous, between 1 and 500\]. A similar model will be fit the total number of differences. The analytical method will be determined by the data and may be liner regression. Predictors: Region-Categorical (6) Population-Continuous Life expectancy-Continuous Infant mortality rate-Continuous GDP per capita-Continuous Health expenditure per capita Inequality-Continuous Corruption Perception Index-Continuous
Interventions
OTHERCountry characteristics
Observational study of country characteristics
Sponsors
Unity Health Toronto
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Countries that have an essential medicines list, and Canada
Exclusion criteria
* countries that do not have an essential medicines list that is available online
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total number of differences between the WHO model list of essential medicines and the essential medicines list in each country | 1 year | The total number of differences between the WHO model list of essential medicines and the essential medicines list in each country is comprised of: 1. number of WHO model list medicines not on country list including the number of substitutions within class (i.e. a medicine on WHO list not on country's list but a similar agent in the same class is on the country's list); and the 2. number of medicines on the country list but not on the WHO model list. |
Secondary
| Measure | Time frame |
|---|---|
| Medications that are on the WHO list but not on the country list | 1 year |
| Medications that are on the country list but not on the WHO list | 1 year |
Countries
Canada
Outcome results
None listed