Growth Retardation, Nutrition Deficiency Due to Insufficient Food, Premature Infants
Conditions
Brief summary
Nutrition is a major issue for premature infants. Inappropriate nutritional intake during the first weeks of life is responsible for postnatal growth restriction and adverse long-term outcomes. This study aimed at evaluating the impact of the introduction of an updated, standardized, nutrition protocol on very premature infants' growth and morbidity, and the care givers' compliance to the new protocol.
Interventions
OTHERnutrition protocol introduction
Growth comparison of 2 cohorts of infants evaluated in a before-after design
Sponsors
Central Hospital, Nancy, France
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Days to 77 Days
Healthy volunteers
No
Inclusion criteria
* All surviving infants born between 26 and 32 weeks gestation in our Level III NICU
Exclusion criteria
* Death * Any congenital malformation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| weight | weekly recording from Day 0 up to Day 77 | longitudinal weight evaluation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| late onset sepsis | Day 77 postnatal age | Incidence of late onset sepsis |
| patent ductus arteriosus | Day 77 postnatal age | Incidence of patent ductus aretriosus requiring treatment |
| Necrotizing enterocolitis | Day 77 postnatal age | Necrotizing enterocolitis |
| Central venous catheters. | Day 77 postnatal age | Duration of central venous catheters |
| Compliance to the protocol | weekly recording from Day 0 up to Day 77 | comparison between expected prescription and actual nutrition intake |
| Bronchopulmonary dysplasia | Day 77 postnatal age | Incidence of Bronchopulmonary dysplasia |
Outcome results
None listed