Anemia
Conditions
Brief summary
Iron deficiency is the most prevalent nutritional deficiency and the most common cause of anemia .It is characterized by a defect in hemoglobin synthesis, resulting in red blood cells that are abnormally small (microcytic) and contain a decreased amount of hemoglobin (hypochromic).
Interventions
DRUGIron dextran
total dose infusion
DRUGFerrous Fumarate
oral tablets
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Hemoglobin \< 10 g/dL * Gestational age between 14-28 weeks. * Willingness to participate and signing the informed consent form.
Exclusion criteria
* Iron overload or disturbances in utilization of iron * Decompensated liver cirrhosis and active hepatitis * Active acute or chronic infections * History of multiple allergies * Known hypersensitivity to parenteral iron or any recipients in the investigation drug products * Erythropoietin treatment within 8 weeks prior to the screening visit * Other iron treatment or blood transfusion within 4 weeks prior to the screening visit * Planned elective surgery during the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change in Hemoglobin concentration from baseline to 8 weeks therapy | 8 weeks | measure hemoglobin level before and after treatment |
Countries
Egypt
Outcome results
None listed