Infertility
Conditions
Brief summary
The aim of this study is to evaluate the effect of treatment of vitamin D deficiency (through vitamin D supplementation for 8 weeks before the start of In-vitro fertilization (IVF) on the success of IVF cycles.
Detailed description
The study participants are vitamin D deficient females undergoing (intra-cytoplasmic sperm injection (ICSI) trial in the age of 20 to 35 years. Serum vitamin D will be assessed. Accordingly, if they are deficient in vitamin D, they will be eligible for the study.400 vitamin D deficient women will be randomly allocated to either one of two groups. The first group will receive vitamin D supplementation in addition to the routine care. The other group will receive the routine care only. The study will be conducted in the IVF unit of department of Obstetrics and Gynecology, Cairo University.
Interventions
DRUGVitamin D
Vitamin D supplement will be given. Then, it will be maintained if pregnancy occurred
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
* Vitamin D deficient females undergoing first ICSI trial * Age from 20 to 35 years
Exclusion criteria
* Women undergoing ICSI trials who are vitamin D sufficient
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical pregnancy rate | It will be calculated 1 year after enrollment of the first patient in the study | This outcome will be calculated by a statistician |
Countries
Egypt
Outcome results
None listed