Cardiac Complication, Death, Heart Diseases, Postoperative Complications
Conditions
Keywords
Cardiac surgery, Thoracic surgery
Brief summary
The registry for the improvement of postoperative outcomes in cardiac and thoracic surgery aims to prospectively collect data in order to test the association between various preoperative and per-operative variables ; and several postoperative outcomes such as mortality, shock, redo surgery, sepsis and extracorporeal life-support.
Detailed description
Cardiac and thoracic surgery is plagued by severe morbidity and mortality. Understanding and being able to predict postoperative outcomes may allow to better fit peri-operative care of cardio-thoracic patients. RIPOSTE database aims to prospectively collect baseline characteristics and per-operative information in order to test associations with the incidence of postoperative outcomes. Baseline characteristics include: age, EuroSCORE 2 and its components (age, gender, New York Heart Association (NYHA) functional class, angina symptoms, insulin-dependent diabetes mellitus, extracardiac arteriopathy, chronic pulmonary dysfunction, neurological or musculoskeletal dysfunction severely affecting mobility, previous cardiac surgery, renal function with creatinin clearance, active endocarditis, critical preoperative state, left ventricle ejection fraction, recent myocardial infarction, pulmonary artery systolic pressure, procedure urgency and weight of the procedure (coronary artery bypass graft, valve surgery and/or thoracic aorta)) weight, height, preoperative biology and preoperative echocardiography parameters when measured. Peroperative information include: cardiac bypass duration, type of procedure, implanted device, valve size. Postoperative outcomes include: death, postoperative shock, mediastinitis, length of stay in intensive care unit, overall length of stay, blood transfusion.
Interventions
PROCEDURECardiothoracic surgery
Cardiac or thoracic procedure
Sponsors
CMC Ambroise Paré
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* all patients eligible for cardiac or thoracic surgery
Exclusion criteria
* non applicable
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| In-hospital mortality | During follow-up, until discharge from hospital, up to 1 year. | death occurring in the same hospital where the operation took place before discharge from the hospital |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative shock | In the first 24 hours after surgery | Use of catecholamines (dobutamine, norepinephrine and/or epinephrine) in order to achieve adequate cardiac output (cardiac index \> 2.2 l/min/m2), in the first 24 hours after surgery |
| Length of stay in the ICU (days) | During follow-up, until discharge from the ICU, up to 1 year. | length of stay in the intensive care unit after cardiac or thoracic surgery |
| Total length of stay (days) | During follow-up, until discharge from the hospital, up to 1 year. | length of stay in the hospital, including preoperative period |
| Mediastinitis | During follow-up, until discharge from the hospital, up to 1 year. | Incidence of mediastinitis in the postoperative period |
| Redo surgery | During follow-up, until discharge from the hospital, up to 1 year. | Redo surgery after primary surgery |
| Pneumoniae | During follow-up, until discharge from the hospital, up to 1 year. | Hospital-acquired or Ventilator-acquired pneumonia as defined by Center for Disease Control guidelines |
Countries
France
Contacts
CONTACTAlain Brusset, MD
CONTACTLee S Nguyen, MD
STUDY_CHAIRMarie-Caroline Merand
CMC Ambroise Paré
Outcome results
None listed