Uncontrolled Hypertension
Conditions
Keywords
Adherence, Therapeutic Drug Monitoring, Patient perspective
Brief summary
The aim of the study is to investigate and explore the most important aspects of drug-adherence in the treatment of hypertension in order to improve treatment and blood pressure control, implying that new knowledge will reduce morbidity and mortality.
Interventions
DIAGNOSTIC_TESTTherapeutic drug monitoring
Therapeutic drug monitoring will be performed.
Patients will perform home blood pressure monitoring at home.
Sponsors
University of Oslo
Haukeland University Hospital
University Hospital of North Norway
St. Olavs Hospital
Oslo University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Signed informed consent * Uncontrolled hypertension * A stable medication regimen for at least 4 weeks of ≥ 2 antihypertensive agents * No planned changes in antihypertensive drugs
Exclusion criteria
* Withdrawal of consent * 24-h systolic ambulatory blood pressure \>/= 170 mmHg * Patients with inadequate Norwegian language skills * Positive pregnancy test * Known alcohol or drug abuse * estimated glomerular filtration rate \<30 mL/min/1.73m2 * Albumin/creatinin ratio \>300 mg/mmol * Any reason why, in the opinion of the investigator, the patient should not participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Blood pressure control | 3 months after baseline | Change in systolic daytime ambulatory blood pressure. |
Countries
Norway
Outcome results
None listed