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Exercise Exposure Data Collection in Patients Undergoing Tumor Molecular Profiling

Exercise Exposure Data Collection in Patients Undergoing Tumor Molecular Profiling

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03208374
Enrollment
1600
Registered
2017-07-05
Start date
2017-06-27
Completion date
2027-06-01
Last updated
2026-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Carcinoma

Keywords

Histologically confirmed cancer, IMPACT testing, 17-327

Brief summary

This study will recruit approximately 5,000 patients with histologically confirmed cancer who have successfully completed MSK-IMPACT panel testing and collect information about tumor genetic results and patient exercise behavior history. The purpose of the study is to create a registry to collect exercise behavior history in patients who had IMPACT genetic panel testing on protocol IRB #12-245 "Genomic Profiling in Cancer Patients", IRB #06-107 "Storage and Research Use of Human Biospecimens," or IRB #09-141 "Collection of Human Biological Specimens from Patients for Research Studies." The investigators want to find a way to create an exercise database. This database will collect information about tumor genetic results and patient exercise behavior history.

Interventions

BEHAVIORALPrior Exercise Behavior Questions - Harvard Health Professionals Exercise Questionnaire

Participants will be asked how often on average over the year prior to their most recent diagnosis they participated in walking or hiking; jogging; running; calisthenics, aerobics, rowing, Nordic track; bicycling; tennis, squash, racquetball; lap swimming; weightlifting; and other aerobic exercise (e.g. heavy outdoor work), as well as their usual walking pace and flights of stairs climbed daily over the past 12 months prior to diagnosis.

BEHAVIORALCurrent Exercise Behavior Questions: International Physical Activity Questionnaire Short Form (IPAQ SF)

The purpose of this questionnaire is to provide common instruments that can be used to obtain internationally comparable data on exercise exposure in adults aged 15 to 80 years old.

Sponsors

Memorial Sloan Kettering Cancer Center
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Cohort 1: IMPACT Cohort Inclusion Criteria: * Histologically-confirmed cancer. * IMPACT testing with completed genomic profile completed within three years of initial recruitment approach * Registered to Memorial Sloan Kettering Cancer Center protocol IRB# 12-245 and/or IRB #06-107 and/or IRB # 09-141 * ≥ 18 years of age * ECOG Performance Status of 0 or 1

Exclusion criteria

* Unable to speak and read English * Not willing to provide informed consent

Design outcomes

Primary

MeasureTime frameDescription
Characterize exercise participant behavior history via exercise surveyUp to 5 yearsParticipants who have undergone MSK-IMPACT panel testing will complete the exercise history survey. The 10 minute survey only asks participants about their exercise history, both in period before their most recent diagnosis as well as their current exercise behavior.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORJessica Scott, PhD

Memorial Sloan Kettering Cancer Center

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 7, 2026