Obstructive Sleep Apnea, Physical Activity
Conditions
Brief summary
Patients with obstructive sleep apnea (OSA) are less physically active than healthy controls. First choice of treatment for OSA is continuous positive airway pressure (CPAP) therapy with an improvement in oxygen saturation and sleep. No improvement on physical activity has been shown. The current study would randomize patients in a standard care group (CPAP) and an intervention group (CPAP + telecoaching). Telecoaching will be performed for 3 months, with physical activity assessment before, after 3 months and 12 years.
Interventions
OTHERTelecoaching
Patients in the intervention arm will receive a step counter and a cell phone with an app on which the amount of steps are daily sent to. Initial targets on steps per day will be discussed with the patient after an activity monitoring before the telecoaching procedure. Dependent whether the patient reaches his/her proposed goal each week, new goals are set.
DEVICECPAP
Patients will receive CPAP according to standard care
Sponsors
Universitaire Ziekenhuizen KU Leuven
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Randomized controlled trial
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* AHI \> 15 events/hour, measured by polysomnography * \< 7,500 steps per day * Willing to start CPAP treatment * Age between 18 and 65 years * Signing the written informed consent
Exclusion criteria
* Patients with neuromuscular diseases * Patients with chronic obstructive pulmonary disease and interstitial lung disease * Patients with cardiac failure and ischemic heart failure * Patients with comorbidities which could interfere with a normal biomechanical gait pattern and the possibility of increasing physical activity * Patients with mental disability making it impossible to understand the study protocol and the use of electronic devices.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in steps per day after 3 months | The change will be measured after 3 months | Steps per day as measured by a step counter |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The proportion of patients with an increase > 1,000 steps per day | After 3 months (end of telecoaching) and after 12 months | — |
| The proportion of patients with > 7500 steps/day | Before initiation of telecoaching (baseline), after 3 months (end of telecoaching) and after 12 months | — |
| Change in functional exercise capacity | 3 months and 12 months compared with baseline | 6-minute walking distance |
| Change in daytime sleepiness | 3 months and 12 months compared with baseline | Epworth Sleepiness Scale |
| Change in endothelial function | 3 months and 12 months compared with baseline | Endo-PAT 2000 measurement |
| Change in body composition | 3 months and 12 months compared with baseline | Bodystat 1500 measurement |
| Change in quality of life | 3 months and 12 months compared with baseline | SF-36 questionnaire |
| Change in steps per day after 12 months | The change will be measured after 12 months | Steps per day as measured by a step counter |
| Change in sleep quality | 3 months and 12 months compared with baseline | Pittsburgh Sleep Quality Index |
Outcome results
None listed