Ultra-trail Participation
Conditions
Keywords
biological markers, mesenteric ischemia, ultratrail
Brief summary
To assess the evolution of biological markers of mesenteric ischemia during ultratrail.
Detailed description
During physical exercise, increased sympathetic nervous system activity redistributes blood flow from splanchnic organs to working muscles. With prolonged duration and / or intensity, the splanchnic blood flow can be reduced by 80% or more. A severely reduced of splanchnic blood flow can frequently cause gastrointestinal ischemia. This ischemia associated with reduced vagal activity probably results in changes in motility and absorption. High symptoms are reported in 40% of runners with reflux and heartburn in 15-20% of runners. The low symptoms have an incidence of about 70% in the long runs type ultra-trail. Biological markers such as I-FABP have been shown to be useful in the diagnosis of mesenteric ischemia.
Interventions
BIOLOGICALBlood analysis
Blood test of biological markers of mesenteric ischemia
Sponsors
University Hospital, Clermont-Ferrand
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Healthy Voluntary Subject * Age \> 18 years * Written consent * Subject affiliated to Social Security * Medical certificate (mandatory to take part in the ultra-trail)
Exclusion criteria
* Refusal to participate * Subject with legal protection (guardianship, trusteeship)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assess biological markers of mesenteric ischemia (IFABP) | at day 1 | during ultratrail. |
Secondary
| Measure | Time frame |
|---|---|
| Relationship between digestive symptoms and biological markers (IFABP). | at day 1 |
Countries
France
Outcome results
None listed