Maternal Serum Amyloid A Levels in Pregnancies Complicated With Preterm Labour.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03205020

Enrollment

Registered

2017-07-02

Start date

2017-07-01

Completion date

2018-02-01

Last updated

2017-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm Labor

Brief summary

The aim of the current study is to assess the accuracy of maternal serum amyloid A for prediction of preterm labor in women with threatened preterm labor.

Interventions

DIAGNOSTIC_TESTserum amyloid a test

* Women who are diagnosed with preterm labor (28-36 weeks) will be enrolled in this study. Serum samples will be collected from all women before any intervention. All women will be sampled once at the time of admission. * Venous blood sample (5 c.c) will be taken from each participant for examination of serum amyloid A. * The collected blood will be centrifuging and serum will be stored to measure the level of amyloid A by (ELISA) technique in clinical pathology department- Ain shams University

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* Pregnant women, age 18 - 35. * Gestational age: 28 - 36+6 weeks. * Singleton pregnancy. * No past history of any medical disorder and with no other medical complications during pregnancy * Nonsmoker. * Diagnosis of preterm labor is based on the American College of Obstetricians and Gynecologists Guidelines Criteria of preterm delivery: 1. Gestational age: 28 - 36+6 weeks 2. Presence of uterine contractions (at least 4 in 20 minutes or 8 in 60 minutes) 3. cervical dilation ≥ 4 cm 4. Cervical effacement ≥ 80%.

Exclusion criteria

* Of any patient with the following risk factors for preterm labor: * Over distended uterus . * hemorrhage * Uterine anomalies

Design outcomes

Primary

Measure	Time frame	Description
prevalence of Amyloid A level in women with preterm labour	6 months	venous sample will be taken from each participant from onset of labour, Amyloid a level will be calculated

Secondary

Measure	Time frame	Description
neonatal complications	6 months	preterm baby will be examined at neonatal intensive care unit by neonatologist. • Admission to Neonates intensive care unit.

Countries

Egypt

Contacts

Primary Contactmona cairo nematallah, MS

drmonanematallah11@gmail.com01061490044

Backup ContactMONA M, MS

newnononew@gmail.com01272207585

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026