Stress Response During Laryngoscopy Intubation
Conditions
Brief summary
Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation With Single Dose of Dexmedetomidine in Hypertensive Patients.
Interventions
DRUGDexmedetomidine
Dexmedetomidine preinduction
DRUGsterile saline
normal saline preinduction
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* \- Age group 20-60 years * ASA grade 1 and 2 * control hypertensive patients.
Exclusion criteria
* \- Consent not given * ASA Grade 3 and 4 * history of myocardial ischemia or infarction, or had an abnormal ECG on admission to the hospital * Patients with cardiovascular, pulmonary, hepatic, and renal disease. * Patients on B blockers. * patients with difficult airway; laryngoscopy and intubation time more than 20 s, or requiring more than two attempts will be exclude from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate | through first 15 min post-induction of anesthesia |
Secondary
| Measure | Time frame |
|---|---|
| systolic blood pressure | through first 15 min post-induction of anesthesia |
| diastolic blood pressure | through first 15 min post-induction of anesthesia |
Countries
Egypt
Outcome results
None listed