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Determinants of Balance Recovery After Stroke - Retrospective Study

Determinants of Balance Recovery After Stroke

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03203109
Acronym
DOBRAS-R
Enrollment
300
Registered
2017-06-29
Start date
2012-01-31
Completion date
2019-10-31
Last updated
2019-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Keywords

lateropulsion, pusher syndrome, posture, balance, PASS, verticality perception, gait

Brief summary

Retrospective cohort study of consecutive patients investigated in a neurorehabilitation ward after a first hemispheric stroke. Postural and gait disorders in relation to referential of verticality have been analyzed in routine care.

Detailed description

300 consecutive patients, admitted in our department for neurorehabilitation after a first hemispherical stroke, have been enrolled retrospectively. During their hospitalisation, all patients have been routinely evaluated with clinical scales, evaluating motor and cognitive deficits. Postural and visual vertical (VV) assessments have been performed 1 to 4 times during in-patient-stay. The objective was to analyse the determinants of balance recovery after stroke, in particular the impact of wrong referential of verticality. Data collection was performed by means of medical records. Observation period covered from january 2012 to february 2018.

Interventions

BEHAVIORALPostural Assessment Scale for Stroke (PASS)

Postural Assessment Scale for Stroke (PASS)

Sponsors

University Hospital, Grenoble
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

first hemispheric stroke patient non-opposed to inclusion

Exclusion criteria

history of neurological disorders interfering with balance history of vestibularly disorders interfering with balance unstable medical conditions history of cognitive disorders

Design outcomes

Primary

MeasureTime frameDescription
Postureadmission and monthly, up to 3 monthsChange from Baseline Score of Postural Assessment Scale for Stroke (PASS) at discharge

Secondary

MeasureTime frameDescription
Fallsat discharge, the number of falls is totalizedMonitoring of falls occuring during the hospitalization
Balanceadmission and monthly, up to 3 monthsAssessment of Balance and Posture with SCP (Scale for Contraversive Pushing)
Gaitadmission and monthly, up to 3 monthsAssessment of Gait with Lindmark test
Postural disordersadmission and monthly, up to 3 monthsAssessment of Postural control with CDP (Computerized posturography)
Visual vertical perceptionadmission and monthly, up to 3 monthsAssessment of the visual vertical (vv). Subject indicates which direction a visual line displayed on a computer screen (in darkness) is perceived as vertical in the roll plane.
Postural vertical perceptionadmission and monthly, up to 3 monthsAssessment of the postural vertical (pv). Subject is seated in a specific device (CE-marked) in darkness, and indicates which direction of her/his whole body is perceived as vertical in the roll plane.
Walking distanceadmission and monthly, up to 3 monthsAssessment of walking distance with the 6-minute-walking-test (6-MWT)
Gait velocityadmission and monthly, up to 3 monthsAssessment of gait velocity at self-prefered-velocity on 10 meters
Pressure sensitivity (Hand and foot)admission and monthly, up to 3 monthsAssessment of hypoesthesia with Semmes-Weinstein monofilaments test
Spasticityadmission and monthly, up to 3 monthsAssessment of Spasticity with Ashworth Scale
Lateralityadmission and monthly, up to 3 monthsAssessment of Laterality with Edinburgh Handedness Inventory
Neuropsychological Assessment 10admission and monthly, up to 3 monthsAssessment of depression with ADRS (Aphasia Depression Rating Scale)
Neuropsychological Assessment 1admission and monthly, up to 3 monthsAssessment of Hemispatial Neglect with the Catherine Bergego Scale (CBS)
Neuropsychological Assessment 2admission and monthly, up to 3 monthsAssessment of Hemispatial Neglect with the fluff Test
Neuropsychological Assessment 3admission and monthly, up to 3 monthsAssessment of Hemispatial Neglect using 'thumb localizing test' (TLT)
Neuropsychological Assessment 4admission and monthly, up to 3 monthsAssessment of Hemispatial Neglect with the 'Comb and Razor Test'
Neuropsychological Assessment 5admission and monthly, up to 3 monthsAssessment of Hemispatial Neglect with the BEN ( Battery of tests for the quantitative assessment of unilateral neglect)
Neuropsychological Assessment 6admission and monthly, up to 3 monthsAssessment of Apraxia with ATS (Apraxia Screen of TULIA)
Neuropsychological Assessment 7admission and monthly, up to 3 monthsAssessment of Language with LAST (Language Screening Test)
Neuropsychological Assessment 8admission and monthly, up to 3 monthsAssessment of Aphasia with BDAE (Boston Diagnostic Aphasia Examination)
Visual field defect (hemianopia/quadranopia)admission and monthly, up to 3 monthsstandardized clinical examination
Identification of brain structures involved in the strokeonce, at 2 monthanatomical MRI
Disabilityadmission and monthly, up to 3 monthsAssessment of Autonomy with FIM (Functional Independence Measure)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026