Magnesium Supplementation in Stress Conditions

Randomized, Double-blind, Placebo-controlled Intervention Study About the Effects of Magnesium Supplementation Using Nutritional Supplements on the Stress Parameters of Students Preparing for Examination

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03203096

Enrollment

Registered

2017-06-29

Start date

2017-01-15

Completion date

2017-06-06

Last updated

2017-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress Physiology

Keywords

magnesium, stress, metabolomics, heart rate variability

Brief summary

This study aims to determine how a 6-week magnesium supplementation with 400 mg magnesium from magnesium citrate/magnesium oxide affects stress parameters in students in exam preparation.

Detailed description

The examinations are carried out in 70 students in exam preparation (6 weeks before exam). The target parameters are determined in blood and 24h-urine. Blood sampling takes place at confinement, after 3 weeks and at the end of the study (week 6). In addition, heart rate variability is determined.

Interventions

DIETARY_SUPPLEMENTMagnesium

Magnesium citrate / Magnesium oxide

DIETARY_SUPPLEMENTPlacebo

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* healthy students in exam preparation

Exclusion criteria

* pregnancy * any chronic diseases

Design outcomes

Primary

Measure	Time frame	Description
blood sampling	6 weeks	measurement of stress metabolites
24h-urine	6 weeks	measurement of stress metabolites
heart rate variability	6 weeks	measurement of heart rate variability

Countries

Slovakia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026