ZipLine Incision Approximation Verses Suture:ZIPS3 Physician Preference Study

ZipLine Incision Approzimation Vs. Suture:Zips3 Physician Preference Study

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03201536

Acronym

ZIPS3

Enrollment

Registered

2017-06-28

Start date

2012-10-31

Completion date

2012-10-31

Last updated

2017-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wounds and Injuries

Keywords

ZipLine3 device vs. conventional sutures

Brief summary

Zipline incision approximation vs. Suture -- zips 3 study. A prospective, multi-site, non-blinded, randomized controlled, study designed to evaluate user preferences associated with use of the zipline 3 system versus conventional suturing for incision closure.

Detailed description

The objective of this study is to evaluate user preferences associated with the ZipLine 3 system versus conventional suture placement.

Interventions

DEVICEconventional Suture

Sutures

DEVICEZip3

wound closure device

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients between 18 and 75 years of age * In generally good health * Willing to be evaluated in 5-14 days and 3-months post op 2. Patient requiring a non-emergent skin incision or biopsy * Maximum excision size 1.5x3.0 cm * Requiring 4-0 or smaller suture for closure * In area of body trunk or extremities with low mobility and tension

Exclusion criteria

1. Facial Incisions or incisions in high stress or tension areas 2. Previously diagnosed peripheral vascular disease 3. Insulin-dependent diabetes mellitus 4. Known bleeding diathesis 5. Known personal or family history of keloid formation or scar hypertrophy 6. Known allergy or hypersensitivity to adhesives 7. Presently taking steroids, immune stimulants, beta blockers, or anticoagulants 8. Atrophic skin deemed clinically prone to blistering 9. Any skin disorder affecting wound healing 10. Incisions requiring dermal sutures 11. Any other condition that in the opinion of the investigator would make a particular patient unsuitable for this study

Design outcomes

Primary

Measure	Time frame	Description
Wound healing	3-month	Wound healing as judged by the CVAS (Cosmetic Visual Analogue Scale) wound healing scale

Secondary

Measure	Time frame	Description
time of procedure	immediately	Time it takes to use device

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026