WEakness and Atrophy: isoKinetic With Surface Electromyography Assessment in ACL Surgery

Motor Unit Recruitment Study With Fatigue Testing: 9 Months Following up After Anterior Cruciate Ligament Surgery.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03200678

Acronym

WEAKNESS

Enrollment

Registered

2017-06-27

Start date

2018-05-07

Completion date

2023-09-30

Last updated

2022-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Cruciate Ligament Injury, Muscle Weakness

Keywords

knee muscle, strength, fatigue, MRI, ACL

Brief summary

An assessment of the effect of surgical anterior cruciate ligament (ACL) on thigh muscles is critical to the improvement of knee rehabilitation and preservation. However, if a large number of studies had rated surgical technics, giving high results level for ACL reconstruction (ACLR), muscle recovery is still conditioning functional success. Furthermore there is no consensus about criteria in return to sport. The aim of this exploratory study is to quantify the mechanisms of neuromuscular adaptation of muscle thigh after ACL surgery.

Detailed description

The aim of this study is to assess the qualitative and quantitative variations of the strength, work and fatigue of the thigh muscles after ACL surgery. The reference is the preoperative assessment (V1), the variation is measured on V2 (measurements at 3 months) and V3 (measures at 9 months). Each patient is his own control. In addition, a control group of healthy subjects is used to determine level of significance of each parameter.

Interventions

OTHERisokinetic assessment

muscle torque assessement

Study design

Allocation

NON_RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

ACLR group : * men or woman * 18 to 45 years old * No injuries sequels on contralateral limb * No contraindication to magnetic resonance imaging Control group : * men or woman * 18 to 45 years old * No limb injuries sequels * No contraindication to magnetic resonance imaging

Exclusion criteria

* age less than 18 years * limb injuries sequels * contraindication to magnetic resonance imaging

Design outcomes

Primary

Measure	Time frame	Description
muscle torque	Change is being assessed between preoperative assessment (V1), measurement at 3 months (V2), measures at 9 months (V3)	Newton.meter (N.m)

Secondary

Measure	Time frame	Description
muscle work	Change is being assessed between preoperative assessment (V1), measurement at 3 months (V2) and measures at 9 months (V3)	Joule (J)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026