ARDS, Extracorporeal Membrane Oxygenation
Conditions
Brief summary
A prospective, observational study will be performed measuring recirculation of blood through a veno-venous Extracoporeal Membrane Oxygenation (vvECMO) in patients with acute respiratory distress syndrome (ARDS) on vvECMO. ECMO blood flow will be adjusted with respect to recirculation.
Interventions
OTHERMeasurment of blood recirculation
Ultrasound based measurments of blood recirculating through the vvECMO circuit.
Sponsors
Charite University, Berlin, Germany
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients aged 18 years or older * ARDS * veno-venous ECMO
Exclusion criteria
* age \< 18 years * hemodynamic instability during measurement of recirculation * pregnancy * inability to obtain patient's consent or consent of legal guardian
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recirculation of vvECMO blood flow | Once within first week after ICU admission during 4 hours | Amount of ECMO blood flow recirculating through the vvECMO circuit |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Reduction of vvECMO blood flow | Once within first week after ICU admission during 4 hours | Reduction of vvECMO blood flow if a significant recirculation can be measured |
| Arterial blood oxygen content after reduction of vvECMO blood flow | Once within first week after ICU admission during 4 hours | Change in arterial blood oygen content after reduction of vvECMO blood flow |
Countries
Germany
Outcome results
None listed