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Water Intake Associated With Aerobic Exercise in Coronary

Influence of Hydration on Autonomic Behavior and Cardiorespiratory Parameters of Coronaropathy Submitted to Aerobic Exercise

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03198806
Enrollment
31
Registered
2017-06-26
Start date
2018-08-25
Completion date
2019-06-25
Last updated
2020-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

Autonomic Nervous System, Fluid Therapy, Heart Rate, Exercise

Brief summary

The need to restore water losses resulting from physical activity has become established and diffused into international consensus for healthy individuals or high-performance athletes. However, the influence of fluid replacement when administered during and after exercise on cardiorespiratory parameters, cardiac autonomic modulation, and subjective perceptions of effort and pain of individuals with autonomic alterations known as the coronary arteries remain poorly understood. In this sense, this study intends to investigate the influence of hydration on cardiac autonomic modulation, cardiorespiratory parameters, subjective perception of exertion and pain of coronary arteries submitted to aerobic exercise in the model of a cardiovascular rehabilitation session. A total of 31 individuals will be recruited in this study and will perform four standardized cardiovascular rehabilitation sessions. Only in the second and the fourth session will the volunteers be instructed to ingest a quantity of water predetermined by the evaluator, based on the loss of body mass measured in the first and the third sessions. The outcomes (autonomic modulation, cardiorespiratory variables and perceptions) will be evaluated before, during and after exercise. The results of this study will enable professionals working with this population to implement awareness strategies on the importance of fluid intake in cardiovascular rehabilitation programs.

Interventions

OTHERTreadmill aerobic exercise in supine position

The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise followed by 60 minutes of recovery at the supine position.

OTHERTreadmill aerobic exercise and water intake in supine position

The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise and water intake followed by 60 minutes of recovery at the supine position.

OTHERTreadmill aerobic exercise in orthostatic position

The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise followed by 10 minutes of recovery at the orthostatic position.

OTHERTreadmill aerobic exercise and water intake in orthostatic position

The volunteers will be submitted to a cardiovascular rehabilitation session with 40 minutes of treadmill aerobic exercise and water intake followed by 10 minutes of recovery at the orthostatic position.

Sponsors

Universidade Estadual Paulista Júlio de Mesquita Filho
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
45 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Men with coronary heart disease ischemia, over 45 years * At least three months of cardiovascular rehabilitation

Exclusion criteria

* smokers, alcoholics * Uncontrolled metabolic disease (eg, uncontrolled diabetes and thyroid diseases) * Abnormal hemodynamic responses during exercise such as disproportionate increase / fall of heart rate and / or blood pressure to low / high levels of load * myocardial ischemia and / or severe ventricular arrhythmias during the exercise test

Design outcomes

Primary

MeasureTime frameDescription
Heart rate variabilityup to six monthsIndices of heart rate variability

Secondary

MeasureTime frameDescription
Subjective Effort Perceptionup to six monthsBorg Scale
Subjective Pain Perceptionup to six monthsBorg CR-10 Scale
Cardiovascular parameterup to six monthsHeart Rate
Cardiorespiratory parameterup to six monthsRespiratory frequency

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026