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The Effect of Enamel Matrix Derivatives on Root Coverage Esthetic Score

The Effect of Enamel Matrix Derivatives on Root Coverage Esthetic Score

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03197610
Enrollment
19
Registered
2017-06-23
Start date
2015-01-01
Completion date
2016-09-01
Last updated
2017-06-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Recession, Periodontal Diseases

Keywords

gingival recession, sub epithelial connective tissue graft, enamel matrix derivatives, root coverage aesthetic score

Brief summary

Subepithelial connective tissue grafts (SCTG) are accepted as the gold standard in covering denuded root surfaces. Combining enamel matrix derivatives (EMD) with periodontoplasic surgical operations is another method in covering denuded root surface. The aim of this study is to compare a SCTG operation group and EMD applied group in addition to SCTG using complete root coverage rate and a newer method root coverage esthetic scoring system (RES).

Detailed description

Background: Subepithelial connective tissue grafts (SCTG) are accepted as the gold standard in covering denuded root surfaces. Combining enamel matrix derivatives (EMD) with periodontoplasic surgical operations is another method in covering denuded root surface. The aim of this study is to compare a SCTG operation group and EMD applied group in addition to SCTG using complete root coverage rate and a newer method root coverage esthetic scoring system (RES). Methods: This is a split-mouth and controlled study. Thirthy-eight Class I or II gingival recession defects at canine teeth were treated in the control (SCTG) (n=19) and test groups (n=19) (SCTG+EMD). The root coverage esthetic score were evaluated by 2 blind periodontists 1 year after the treatment using RES. The agreement between the two periodontists was assessed by kappa analysis. Complete root coverage rate was evaluated for both groups. Two groups were compared with statistically methods in terms of RES parameters and gingival recession height /width.

Interventions

enamel matrix derivatives and subepithelial connective tissue grafts

Sponsors

Yuzuncu Yil University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Eligibility

Healthy volunteers
No

Inclusion criteria

* The patient had no systemic disease, did not smoke cigarette and tobacco products, did not have a pregnancy and breastfeeding period, had class I and class II gingival recession according to the Miller gingival classification, had a recession depth of ≥2 mm, have not had a restoration and have had an operation in the relevant dental region that had no previous gingival surgical procedure were included in this study.

Exclusion criteria

* systemic disease * multiple gingival recession * miller class III and IV recessions were excluded

Design outcomes

Primary

MeasureTime frameDescription
root coverage percentage1 yearroot coverage percentage of denuded root surface
root coverage aesthetic score1 yearroot coverage aesthetic score of treatment modalities

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026